The Potential of Proton Therapy for Locally Advanced Breast Cancer: Clinical and Technical Considerations

Proton therapy is a promising therapeutic modality with unique physical properties that allow for abrupt dose fall-off distal to the target of interest, thereby sparing nearby organs at risk. A number of studies have identified the utility of proton radiation in mitigating treatment related sequelae...

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Bibliographic Details
Published in:Current oncology (Toronto) 2023-02, Vol.30 (3), p.2869-2878
Main Authors: Lalani, N, Alqarni, S, Jimenez, R B
Format: Article
Language:English
Subjects:
Breast cancer
Breast Neoplasms - radiotherapy
Care and treatment
Female
Health aspects
Humans
proton therapy
Proton Therapy - adverse effects
Protons
Radiation
Radiotherapy
Review
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Summary:Proton therapy is a promising therapeutic modality with unique physical properties that allow for abrupt dose fall-off distal to the target of interest, thereby sparing nearby organs at risk. A number of studies have identified the utility of proton radiation in mitigating treatment related sequelae for patients with locally advanced breast cancers. Thus, in the following review, we highlight clinical and technical considerations for proton radiotherapy delivery in patients with locally advanced breast cancer.
ISSN:1718-7729
1198-0052
1718-7729
DOI:10.3390/curroncol30030219