Outcome after loop electrosurgical excision procedure for cervical high-grade squamous intraepithelial lesion

The dilemma in treating cervical high-grade squamous intraepithelial lesion (HSIL) is how to achieve complete excision to minimize the risk of cervical cancer while sparing the anatomy of the cervix and its ability to function during pregnancy. The optimal management for positive margins after excis...

Full description

Saved in:
Bibliographic Details
Published in:Taiwanese journal of obstetrics & gynecology 2023-01, Vol.62 (1), p.45-49
Main Authors: Kwok, Shuk Tak, Chan, Karen K.L., Tse, Ka Yu, Chu, Mandy M.Y., Lau, Lesley S.K., Ngan, Hextan Y.S., Ngu, Siew-Fei
Format: Article
Language:English
Subjects:
Cervical dysplasia
Colposcopy
Conisation
LEEP
LLETZ
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The dilemma in treating cervical high-grade squamous intraepithelial lesion (HSIL) is how to achieve complete excision to minimize the risk of cervical cancer while sparing the anatomy of the cervix and its ability to function during pregnancy. The optimal management for positive margins after excisional treatment is still controversial. This study was conducted to determine the clinical and histologic predictors of residual/recurrent HSIL and assess the outcome of women with positive margin. This retrospective cohort study included 386 women who had excisional treatment for HSIL during 1st January 2012 to 31st December 2015 in a university-affiliated hospital. Overall, 212 (54.9%) women had negative margins and 155 (40.2%) had positive margins. The cumulative rate of residual/recurrent HSIL at 2 and 5 years was 15.7% and 16.8% respectively in positive margins and 1.8% and 5.0% respectively in negative margins (p 
ISSN:1028-4559
DOI:10.1016/j.tjog.2022.10.004