Group B streptococcal colonization in mothers and infants in western China: prevalences and risk factors

• Published in: BMC infectious diseases 2018-07, Vol.18 (1), p.291-291, Article 291
• Main Authors: Chen, Jichang, Fu, Jinjian, Du, Wei, Liu, Xin, Rongkavilit, Chokechai, Huang, Xuemei, Wu, Yubi, Wang, Yuanliu, McGrath, Eric
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Anti-Bacterial Agents; Antibiotics; Babies; Childrens health; China; Colonization; Demographics; Demography; Development and progression; Disease; Disease prevention; Disease transmission; Distribution; Ear; Ear canal; Early onset disease (EOD); Epidemiology; Female; Fever; GBS colonization; Group B streptococcus; Hospitals; Humans; Infant, Newborn; Infants; Infections; Infectious Disease Transmission, Vertical; Intensive care; Labor; Male; Maternal & child health; Minority & ethnic groups; Mother-infant pairs; Mothers; Nasopharynx; Nasopharynx - microbiology; Neonates; Newborn babies; Pediatrics; Polymerase chain reaction; Pregnancy; Pregnancy Complications, Infectious - epidemiology; Prevalence; Prospective Studies; Rectum - microbiology; Regression analysis; Risk analysis; Risk Factors; Rupture; Rupturing; Statistical analysis; Streptococcal infections; Streptococcal Infections - epidemiology; Streptococcus; Streptococcus agalactiae; Streptococcus infections; Vagina - microbiology; Womens health; Young Adult
• ISSN: 1471-2334; 1471-2334
• DOI: 10.1186/s12879-018-3216-4

The epidemiology of maternal and infant Group B streptococcus (GBS) colonization is poorly understood in China. The aim of this study is to explore the prevalence and risk factors associated with maternal and infant GBS colonization in Western China. From January 2017 to June 2017, a prospective study was conducted to estimate the maternal and infant GBS colonization rate by maternal rectovaginal and infant nasopharynx, ear canal and umbilical swab culture. Patient demographics, clinical characteristics and outcomes were collected. Chi-square and logistic regression analyses were used to examine the risk factors associated with GBS colonization of mothers and infants. The GBS colonization rate in mothers and infants was 6.1 and 0.7%, respectively. The vertical transmission rate was 7.6%. The early onset GBS infection rate was 0.58 per 1000 live births and mortality was 0.29 per 1000 live births. Age younger than 40 years (p = 0.040) and minority ethnic status (p = 0.049) were associated with higher GBS colonization rate in pregnant women. Positive GBS status in the mother prior to delivery (p