Investigation of Chemical Compositions and Biological Activities of Mentha suaveolens L. from Saudi Arabia

• Published in: Molecules (Basel, Switzerland) Switzerland), 2022-05, Vol.27 (9), p.2949
• Main Authors: Aldogman, Bashayr, Bilel, Hallouma, Moustafa, Shaima Mohamed Nabil, Elmassary, Khaled F, Ali, Hazim M, Alotaibi, Faddaa Qayid, Hamza, Mohamed, Abdelgawad, Mohamed A, El-Ghorab, Ahmed H
• Format: Article
• Language: English
• Subjects: Acids; Antifungal activity; Antifungal Agents - chemistry; antioxidant; Antioxidants; Antioxidants - chemistry; Carvone; Chemical composition; Constituents; Drying; Essential oils; Flame ionization detectors; Fungicides; Gas chromatography; Gas Chromatography-Mass Spectrometry; High performance liquid chromatography; Hydrocarbons; Investigations; Ionization; Liquid chromatography; Mass spectrometry; Mass spectroscopy; Mentha; Mentha - chemistry; Mentha suaveolens; Mentha suaveolens L; Miconazole; Oils, Volatile - chemistry; Phenolic compounds; Phenols; Plant Extracts - chemistry; Plant Extracts - pharmacology; Rosmarinic acid; Saudi Arabia; Stems
• ISSN: 1420-3049; 1420-3049
• DOI: 10.3390/molecules27092949

is an aromatic plant used since antiquity for its pharmaceutical virtues. The climate of Saudi Arabia favors the growth of aromatic plants including L. The aim of this study is to analyze the volatile oils of different parts of fresh and dried L. grown in Saudi Arabia (Aljouf area) using Gas Chromatography/Mass Spectrometry (GC/MS) and Gas Chromatography Flame Ionization Detector (GC/FID) techniques, to recognize the effect of drying on chemical composition, then to evaluate the antioxidant and antifungal activities of different extracts. In total, 118 compounds were identified via GC/MS and GC/FID, in which carvone is the main volatile constituent (stems, leaves, whole plant 45-64%). This investigation deduces that belonged to the carvone chemotype. Then, the analysis of non-volatile constituents of fresh and dried was performed by HPLC. The main phenolic compound of fresh and dried for different parts was rosmarinic acid (ranging from 28,002.5 to 6558 µg/g). The ethanolic extract of fresh stem showed the highest antifungal activity (53% inhibition) compared with miconazole (60% inhibition) but the ethanoic extract of dry stem showed no activity. Additionally, all ethanolic extracts, whether for fresh or dry , have antioxidant activity more than 90% while the antioxidant activity of whole plant volatile oil is equal to 53.33%. This research shows that L. could be applied to manufacture natural antioxidants, antifungal, and flavoring agents.