A COVID-19 Overview and Potential Applications of Cell Therapy

The COVID-19 pandemic has already reaped thousands of lives, although many scientific studies already showed the possibility of this scenario. Currently, further attention is provided to patients depicting comorbidities such as respiratory or immunocompromised diseases, hypertension, and diabetes, a...

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Published in:Biologics (Basel, Switzerland) Switzerland), 2021-08, Vol.1 (2), p.177-188
Main Authors: Câmara, Diana Aparecida Dias, Porcacchia, Allan Saj, Lizier, Nelson Foresto, De-Sá-Júnior, Paulo Luiz
Format: Article
Language:English
Subjects:
cell therapy
Coronaviruses
COVID-19
hematologic disease
SARS-CoV-2
stem cell
Viral infections
Viruses
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Summary:The COVID-19 pandemic has already reaped thousands of lives, although many scientific studies already showed the possibility of this scenario. Currently, further attention is provided to patients depicting comorbidities such as respiratory or immunocompromised diseases, hypertension, and diabetes, as these individuals show a worse prognosis. Cell therapies using stem cells and/or defense cells, combined or not with traditional treatment, could be an outstanding strategy for COVID-19 management since these treatments can act by modulating the immune system, reducing proliferation, and favoring the complete elimination of the virus. In this review, we highlight the main molecular characteristics of this novel coronavirus, as well as the main pathognomonic signs of COVID-19. Furthermore, possible cell therapies are pointed out to show alternative treatments against COVID-19 and its sequels.
ISSN:2673-8449
2673-8449
DOI:10.3390/biologics1020011