Hypothalamic transcriptome profile from laying period to incubation period of Changshun green-shell laying hens

Incubation behavior in chickens is closely associated with hypothalamus. Here, RNA sequencing of hypothalamus from Changshun green-shell laying hens, an indigenous chicken breed from China, in egg-laying period (LP) and incubation period (BP) was conducted to identify critical pathways and candidate...

Full description

Saved in:
Bibliographic Details
Published in:Poultry science 2024-08, Vol.103 (8), p.103950, Article 103950
Main Authors: Chen, Zhi, Wen, Di, Cen, Jian, Mu, Ren
Format: Article
Language:English
Subjects:
Animals
Avian Proteins - genetics
Avian Proteins - metabolism
Changshun green-shell laying hen
Chickens - genetics
Chickens - metabolism
Chickens - physiology
Female
Gene Expression Profiling - veterinary
hypothalamus
Hypothalamus - metabolism
incubation period
laying period
Oviposition
PHYSIOLOGY AND REPRODUCTION
Transcriptome
transcriptome analysis
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Incubation behavior in chickens is closely associated with hypothalamus. Here, RNA sequencing of hypothalamus from Changshun green-shell laying hens, an indigenous chicken breed from China, in egg-laying period (LP) and incubation period (BP) was conducted to identify critical pathways and candidate genes involved in controlling the incubation behavior in hypothalamus. A total of 637 up-regulated and 305 down-regulated differently expressed genes (DEGs) were identified in chicken hypothalamus between LP and BP groups. Gene ontology term (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis further revealed that neuroactive ligand-receptor interaction, hippo signaling pathway, and focal adhesion were significantly enriched. Five candidate genes (POMC, IGF1R, CHAD, VCL, and MYL9) were suggested to play crucial roles in the regulation of chicken incubation behavior. Our results further indicated the complexity of reproductive behavior of different chicken breeds.
ISSN:0032-5791
1525-3171
1525-3171
DOI:10.1016/j.psj.2024.103950