Severe meningoencephalitis co-infection due to Cryptococcus neoformans and Mycobacterium tuberculosis in a child with systemic lupus erythematosus

Highlights • Patient had a direct family member with TB and a suspicious CT scan. • We decide to perform PCR to the CSF looking forward to mycobacterial infection. • MRI showed images compatible with typical perivascular hypoxic-ischemic lesions seen in cryptococcosis. • Typical TB images had been d...

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Bibliographic Details
Published in:International journal of infectious diseases 2015-04, Vol.33 (C), p.106-108
Main Authors: Martinez-Longoria, Cesar Adrián, Rubio-Perez, Nadina Eugenia, Rios-Solis, Josue Emmanuel, Garcia-Rodriguez, Fernando
Format: Article
Language:English
Subjects:
Amphotericin B - therapeutic use
Antitubercular Agents - therapeutic use
Child
Co-infection
Coinfection - cerebrospinal fluid
Coinfection - complications
Coinfection - drug therapy
Cryptococcosis - cerebrospinal fluid
Cryptococcosis - complications
Cryptococcosis - drug therapy
Cryptococcus
Cryptococcus neoformans - isolation & purification
Ethambutol - therapeutic use
Female
Humans
Immunocompromised Host
Infectious Disease
Isoniazid - therapeutic use
Lupus Erythematosus, Systemic - complications
Lupus Erythematosus, Systemic - drug therapy
Meningoencephalitis - complications
Meningoencephalitis - drug therapy
Meningoencephalitis - microbiology
Mycobacterium tuberculosis - isolation & purification
Pulmonary/Respiratory
Pyrazinamide - therapeutic use
Rifampin - therapeutic use
Systemic lupus erythematosus
Tuberculosis
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Summary:Highlights • Patient had a direct family member with TB and a suspicious CT scan. • We decide to perform PCR to the CSF looking forward to mycobacterial infection. • MRI showed images compatible with typical perivascular hypoxic-ischemic lesions seen in cryptococcosis. • Typical TB images had been described as tuberculomas (round, peripheral, well circumscribed with contrast enhancement). • Some papers reported TB images appearance similar to those seen in cryptococcosis.
ISSN:1201-9712
1878-3511
DOI:10.1016/j.ijid.2014.05.033