High burden of rheumatic heart disease confirmed by echocardiography among Pacific adults living in New Zealand

• Published in: Open heart 2023-04, Vol.10 (1), p.e002253
• Main Authors: Webb, Rachel, Culliford-Semmens, Nicola, ChanMow, Andrew, Doughty, Robert, Tilton, Elizabeth, Peat, Briar, Stirling, John, Gentles, Thomas L, Wilson, Nigel J
• Format: Article
• Language: English
• Subjects: Adult; Ambulatory Care Facilities; Brochures; Cardiology; Cardiovascular disease; Child; Cross-Sectional Studies; Diabetes; Disease prevention; Echocardiography; epidemiology; Family medical history; global burden of disease; Health Care Delivery, Economics and Global Health Care; Heart; Humans; Hypertension; mitral valve insufficiency; New Zealand - epidemiology; Penicillin; Population; Primary care; Rheumatic fever; Rheumatic Heart Disease - diagnostic imaging; Rheumatic Heart Disease - epidemiology; Teenagers; Ultrasonic imaging; Young adults
• ISSN: 2053-3624; 2398-595X; 2053-3624
• DOI: 10.1136/openhrt-2023-002253

BackgroundDespite numerous echocardiographic screening studies of children in high incidence acute rheumatic fever (ARF)/rheumatic heart disease (RHD) communities, little is known about the prevalence of RHD in adults in these populations.We sought to determine the prevalence of RHD in an urban area of South Auckland, New Zealand, where previous studies had shown the prevalence of RHD in children to be around 2%.MethodsA cross-sectional screening study was conducted between 2014 and 2016. Echocardiography clinics were conducted at an urban Pacific-led primary healthcare clinic in New Zealand. Eligible persons aged 16–40 years were recruited according to a stratified randomised approach. Echocardiograms were performed with a standardised image acquisition protocol and reported by cardiologists.ResultsThere were 465 individuals who underwent echocardiograms. The overall prevalence of RHD (define and borderline) was 56 per 1000 (95% CI 36 to 78 per 1000). Definite RHD was found in 10 individuals (4 of whom were already under cardiology review at a hospital clinic) with a prevalence of 22 per 1000 (95% CI 9 to 36 per 1000). Non-rheumatic cardiac abnormalities were found in 29 individuals.ConclusionsThere is a high burden of both rheumatic and non-rheumatic cardiac abnormalities in this population. Rates described in New Zealand are as high as lower-middle-income countries in Africa. Addressing knowledge gaps regarding the natural history of RHD detected by echocardiography in adults is a priority issue for the international RHD community.