Value of Troponin Testing for Detection of Heart Disease in Previously Healthy Children

Background Troponin levels are frequently obtained in pediatric patients, but the benefit remains unclear. Methods and Results This retrospective study included 1993 patients aged 0 to 21 years without history of cardiac disease in whom troponin levels were obtained during clinical evaluation of car...

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Bibliographic Details
Published in:Journal of the American Heart Association 2020-02, Vol.9 (4), p.e012897-e012897
Main Authors: Dionne, Audrey, Kheir, John N, Sleeper, Lynn A, Esch, Jesse J, Breitbart, Roger E
Format: Article
Language:English
Subjects:
Adolescent
Age Factors
Biomarkers - blood
Brief Communication
chest pain
Child
Child, Preschool
children
Diagnosis, Differential
Female
Heart Disease Risk Factors
Heart Diseases - blood
Heart Diseases - diagnosis
Humans
Infant
Infant, Newborn
Male
Predictive Value of Tests
reference value
Reproducibility of Results
Retrospective Studies
troponin
Troponin - blood
Up-Regulation
Young Adult
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Summary:Background Troponin levels are frequently obtained in pediatric patients, but the benefit remains unclear. Methods and Results This retrospective study included 1993 patients aged 0 to 21 years without history of cardiac disease in whom troponin levels were obtained during clinical evaluation of cardiac and noncardiac presentations. Troponin was elevated (≥0.1 ng/mL) in 182 patients (9%). A cardiac diagnosis was made in 109 (60%) of those with elevated troponin and in 208 (12%) of those without (
ISSN:2047-9980
2047-9980
DOI:10.1161/JAHA.119.012897