Long-Term Efficacy and Tolerability of Abdominal Once-Yearly Histrelin Acetate Subcutaneous Implants in Patients with Advanced Prostate Cancer

Objectives. Long-term assessment of the efficacy and tolerability of subcutaneous abdominal histrelin acetate implants that have been inserted for more than two years. Materials and Methods. Retrospective data collected over a six-year period at a single center from charts of 113 patients who receiv...

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Bibliographic Details
Published in:Prostate Cancer 2014-01, Vol.2014 (2014), p.103-107
Main Authors: Siami, Paul F., Nesbitt, Emily, Holzmeyer, Cameron, Woolen, Sean
Format: Article
Language:English
Subjects:
Abdomen
Androgens
Complications and side effects
Dosage and administration
Hydrogels
Pharmaceuticals
Prostate cancer
Studies
Testosterone
Transplants & implants
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Summary:Objectives. Long-term assessment of the efficacy and tolerability of subcutaneous abdominal histrelin acetate implants that have been inserted for more than two years. Materials and Methods. Retrospective data collected over a six-year period at a single center from charts of 113 patients who received the subcutaneous abdominal histrelin acetate implant. Results. Following insertion of the first implant, 92.1% and 91.8% of patients had a serum testosterone level of ≤30 ng/dL at 24 and 48 weeks, respectively. Serum testosterone levels remained at
ISSN:2090-3111
2090-312X
DOI:10.1155/2014/490315