Acquired long QT syndrome and Torsades de Poin

Acetylcholinesterase inhibitors are group of drugs commonly used in Alzheimer disease and have beneficial effects on treatment. Although they have many known side effects, cardiovascular side effects are rarely seen. We present a 84 year old female who was admitted to emergency service due to repeti...

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Published in:The Egyptian heart journal 2016-09, Vol.68 (3), p.197-199
Main Authors: Ahmet Seyfeddin Gurbuz, Semi Ozturk, Emrah Acar, Süleyman Çagan Efe, Taylan Akgun, Alev Kilicgedik, Ahmet Guler, Cevat Kirma
Format: Article
Language:English
Subjects:
AChIs
Donepezil
QT prolongation
Syncope
Torsades de Pointes
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container_end_page 199
container_issue 3
container_start_page 197
container_title The Egyptian heart journal
container_volume 68
creator Ahmet Seyfeddin Gurbuz
Semi Ozturk
Emrah Acar
Süleyman Çagan Efe
Taylan Akgun
Alev Kilicgedik
Ahmet Guler
Cevat Kirma
description Acetylcholinesterase inhibitors are group of drugs commonly used in Alzheimer disease and have beneficial effects on treatment. Although they have many known side effects, cardiovascular side effects are rarely seen. We present a 84 year old female who was admitted to emergency service due to repetitive syncope episodes while taking donepezil. Her electrocardiogram showed QT prolongation and on follow-up a Torsades de Pointes episode occurred. Patient was discharged with normal corrected QT time after removal of donepezil.
doi_str_mv 10.1016/j.ehj.2015.07.004
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ispartof The Egyptian heart journal, 2016-09, Vol.68 (3), p.197-199
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subjects AChIs
Donepezil
QT prolongation
Syncope
Torsades de Pointes
title Acquired long QT syndrome and Torsades de Poin
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