2-Hydroxy-N′-(4-fluorobenzoyl)benzohydrazide

2-Hydroxy-N′-(4-fluorobenzoyl)benzohydrazide was synthesized in two steps using methyl salicylate as the starting material. The reaction took place via microwave-aided hydrazinolysis, followed by acylation using 4-fluorobenzoyl chloride at low temperature to yield the target compound.

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Bibliographic Details
Published in:MolBank 2020-03, Vol.2020 (1), p.M1103
Main Authors: Santosa, Harry, Yuniarta, Tegar Achsendo, Kesuma, Dini, Putra, Galih Satrio
Format: Article
Language:English
Subjects:
benzoylsalicylhydrazide
methyl salicylate
microwave-assisted synthesis
nucleophilic substitution
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Description
Summary:2-Hydroxy-N′-(4-fluorobenzoyl)benzohydrazide was synthesized in two steps using methyl salicylate as the starting material. The reaction took place via microwave-aided hydrazinolysis, followed by acylation using 4-fluorobenzoyl chloride at low temperature to yield the target compound.
ISSN:1422-8599
1422-8599
DOI:10.3390/M1103