Different levels of physical activity and risk of developing type 2 diabetes among adults with prediabetes: a population-based cohort study

This study aimed to evaluate the association between different levels of physical activity and risk of developing type 2 diabetes (T2D) mellitus among adults with prediabetes in Chinese population. This prospective population-based cohort study included 12,424 participants (mean [SD] age, 52.8 [16.8...

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Bibliographic Details
Published in:Nutrition journal 2024-09, Vol.23 (1), p.107-10, Article 107
Main Authors: Yang, Wenchang, Wu, Yuntao, Chen, Yue, Chen, Shuohua, Gao, Xiang, Wu, Shouling, Sun, Liang
Format: Article
Language:English
Subjects:
Adult
Aged
Blood Glucose - metabolism
Care and treatment
China - epidemiology
Cohort Studies
Development and progression
Diabetes Mellitus, Type 2 - epidemiology
Evaluation
Exercise
Exercise - physiology
Female
Follow-Up Studies
Health aspects
Humans
Incidence
Male
Middle Aged
Physical activity
Physical fitness
Prediabetes
Prediabetic state
Prediabetic State - epidemiology
Prevention
Prospective Studies
Prospective study
Risk Factors
Surveys and Questionnaires
Type 2 diabetes
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Summary:This study aimed to evaluate the association between different levels of physical activity and risk of developing type 2 diabetes (T2D) mellitus among adults with prediabetes in Chinese population. This prospective population-based cohort study included 12,424 participants (mean [SD] age, 52.8 [16.8] years; 82.2% men) with prediabetes at 2014 survey of the Kailuan study. Physical activity information was collected through the International Physical Activity Questionnaire-Short Form and categorized by metabolic equivalent (MET) of task as low, moderate, and high. Cox regression models were built to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for associations between physical activity levels and incident T2D. During a median follow-up of 3.6 years, 2,207 (17.8%) participants developed T2D. The incident rate of T2D were 55.83/1000, 35.14/1000, and 39.61/1000 person-years in the low, moderate, and high physical activity level group, respectively. Both moderate (HR 0.57, 95% CI 0.49 to 0.67) and high (HR 0.76, 95% CI 0.66 to 0.89) physical activity levels were associated with lower risks of developing T2D compared to low physical activity level (P for trend 
ISSN:1475-2891
1475-2891
DOI:10.1186/s12937-024-01013-4