Non-malarial infectious diseases of antenatal care in pregnant women in Franceville, Gabon

• Published in: BMC pregnancy and childbirth 2017-06, Vol.17 (1), p.185-185, Article 185
• Main Authors: Pegha Moukandja, Irene, Ngoungou, Edgard Brice, Lemamy, Guy Joseph, Bisvigou, Ulrick, Gessain, Antoine, Toure Ndouo, Fousseyni S, Kazanji, Mirdad, Lekana-Douki, Jean Bernard
• Format: Article
• Language: English
• Subjects: Acquired immune deficiency syndrome; Adolescent; Adult; AIDS; Antenatal care; Coinfection - epidemiology; Female; Gabon - epidemiology; Health risk assessment; HIV; HIV Infections - epidemiology; HTLV-I Infections - epidemiology; HTLV1; Human health and pathology; Human immunodeficiency virus; Humans; Infectious diseases; Life Sciences; Microbiology and Parasitology; Middle Aged; Mortality; Pregnancy; Pregnancy Complications, Infectious - epidemiology; Pregnant women; Prenatal Care; Prevalence; Retrospective Studies; Rubella - epidemiology; Rubella virus; Santé publique et épidémiologie; Seroepidemiologic Studies; Syphilis - epidemiology; Toxoplasmosis; Toxoplasmosis - epidemiology; Troponema pallidum; Womens health; Young Adult
• ISSN: 1471-2393; 1471-2393
• DOI: 10.1186/s12884-017-1362-0

In sub-tropical countries, infectious diseases remain one of the main causes of mortality. Because of their lack of active immunity, pregnant women and their unborn children represent the most susceptible people. In Gabon, data on infectious diseases of pregnant women such as syphilis and rubella are either scarce or very old. Few studies have assessed T. gondii infection during pregnancy in the country. Here, we evaluate seroprevalence of HIV, HTVL-1, syphilis and T. gondii and rubella infection during antenatal care among women living in Franceville, Gabon. A retrospective study was conducted on data collected from May 2007 to July 2010. After signing an informed written consent form, all pregnant women consulting in two hospitals of Franceville (Gabon) and in offices of maternity and childbirth health centers were included. Demographic and clinical data were collected. Serum samples were collected and analysed using immunological assays relevant for HIV (Genscreen HIV-1 version 2, Bio-Rad®, Marne la Roquette, France).HTLV-1 (Vironostika HTLV-1, Biomérieux®, Marcy l'Etoile, France), T. pallidum (TPHA/VDRL), BIOLABO®SA), rubella virus (Vidas Biomerieux®, Marcy l'Etoile, France) and T. gondii (Vidas Biomerieux®, Marcy l'Etoile, France) diagnoses were performed. Data analysis was done using the Stat view 5.0 software. A total of 973 pregnant women were assessed. The mean age was 25.84 ± 6.9 years, with a minimum age of 14.0 years and a maximum of 45.0 years. Women from 26 to 45 years old and unemployed women were the most prevalent: 41.93% and 77.18%, respectively. The prevalence of studied infectious diseases were 2.50% for syphilis, 2.88% for HTLV-1, 4.00% for HIV with no significant difference between them (p = 0.1). Seropositivity against rubella was higher (87.56%, n = 852) than seropositivity against T. gondii (57.35%, n = 557), (p