Age-Bilirubin-International Normalized Ratio (INR)-Creatinine (ABIC) Score, a Potential Prognostic Model for Long-Term Mortality of CAD Patients After PCI

Given that age, international normalized ratio (INR), total bilirubin, and creatinine are reported to be independent risk factors for predicting outcome in patients with coronary artery disease (CAD), it is possible that the age-bilirubin-INR-creatinine (ABIC) score might be a potential prognostic m...

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Published in:Journal of inflammation research 2023-01, Vol.16, p.333-341
Main Authors: Wu, Ting-Ting, Pan, Ying, Zheng, Ying-Ying, Yang, Yi, Hou, Xian-Geng, Deng, Chang-Jiang, Ma, Yi-Tong, Xie, Xiang
Format: Article
Language:English
Subjects:
Age
age-bilirubin-international normalized ratio -creatinine (abic) score
Bilirubin
Biomarkers
Blood pressure
Cardiovascular disease
Coronary artery disease
Coronary vessels
Creatinine
Death
Diabetes
Heart
Heart attacks
Heart diseases
Hepatitis
Hypertension
Medical prognosis
Mortality
Original Research
prognosis
Regression analysis
Risk factors
Vein & artery diseases
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Summary:Given that age, international normalized ratio (INR), total bilirubin, and creatinine are reported to be independent risk factors for predicting outcome in patients with coronary artery disease (CAD), it is possible that the age-bilirubin-INR-creatinine (ABIC) score might be a potential prognostic model for patients with CAD. A total of 6046 CAD patients after percutaneous coronary intervention (PCI) from the retrospective cohort study (Identifier: ChiCTR-ORC-16010153) were evaluated finally. The primary outcome long-term mortality and secondary endpoints mainly major adverse cardiovascular and cerebrovascular events (MACCEs) were recorded. Multivariate Cox regression models were used to determine risk factors for mortality and MACCEs. The ABIC score was significantly higher in the death group than in the survival group. After adjusting for other CAD risk factors, the ABIC score was identified to be an independent risk factor for long-term mortality by multivariate Cox analysis. When in the high ABIC group, the incidence of all-cause mortality would increased 1.7 times (adjusted HR=1.729 (1.347-2.218),
ISSN:1178-7031
1178-7031
DOI:10.2147/JIR.S394502