Age-Bilirubin-International Normalized Ratio (INR)-Creatinine (ABIC) Score, a Potential Prognostic Model for Long-Term Mortality of CAD Patients After PCI

Given that age, international normalized ratio (INR), total bilirubin, and creatinine are reported to be independent risk factors for predicting outcome in patients with coronary artery disease (CAD), it is possible that the age-bilirubin-INR-creatinine (ABIC) score might be a potential prognostic m...

Full description

Saved in:
Bibliographic Details
Published in:Journal of inflammation research 2023-01, Vol.16, p.333-341
Main Authors: Wu, Ting-Ting, Pan, Ying, Zheng, Ying-Ying, Yang, Yi, Hou, Xian-Geng, Deng, Chang-Jiang, Ma, Yi-Tong, Xie, Xiang
Format: Article
Language:English
Subjects:
Age
age-bilirubin-international normalized ratio -creatinine (abic) score
Bilirubin
Biomarkers
Blood pressure
Cardiovascular disease
Coronary artery disease
Coronary vessels
Creatinine
Death
Diabetes
Heart
Heart attacks
Heart diseases
Hepatitis
Hypertension
Medical prognosis
Mortality
Original Research
prognosis
Regression analysis
Risk factors
Vein & artery diseases
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c475t-930d63b067dab0d76ef4a3537ed5945aab9c434c4e007a198bc49ca31c7ffb393
cites cdi_FETCH-LOGICAL-c475t-930d63b067dab0d76ef4a3537ed5945aab9c434c4e007a198bc49ca31c7ffb393
container_end_page 341
container_issue
container_start_page 333
container_title Journal of inflammation research
container_volume 16
creator Wu, Ting-Ting
Pan, Ying
Zheng, Ying-Ying
Yang, Yi
Hou, Xian-Geng
Deng, Chang-Jiang
Ma, Yi-Tong
Xie, Xiang
description Given that age, international normalized ratio (INR), total bilirubin, and creatinine are reported to be independent risk factors for predicting outcome in patients with coronary artery disease (CAD), it is possible that the age-bilirubin-INR-creatinine (ABIC) score might be a potential prognostic model for patients with CAD. A total of 6046 CAD patients after percutaneous coronary intervention (PCI) from the retrospective cohort study (Identifier: ChiCTR-ORC-16010153) were evaluated finally. The primary outcome long-term mortality and secondary endpoints mainly major adverse cardiovascular and cerebrovascular events (MACCEs) were recorded. Multivariate Cox regression models were used to determine risk factors for mortality and MACCEs. The ABIC score was significantly higher in the death group than in the survival group. After adjusting for other CAD risk factors, the ABIC score was identified to be an independent risk factor for long-term mortality by multivariate Cox analysis. When in the high ABIC group, the incidence of all-cause mortality would increased 1.7 times (adjusted HR=1.729 (1.347-2.218),
doi_str_mv 10.2147/JIR.S394502
format article
fullrecord <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_c726ec11034d4ccd9ae427246fdbc291</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_c726ec11034d4ccd9ae427246fdbc291</doaj_id><sourcerecordid>2771940626</sourcerecordid><originalsourceid>FETCH-LOGICAL-c475t-930d63b067dab0d76ef4a3537ed5945aab9c434c4e007a198bc49ca31c7ffb393</originalsourceid><addsrcrecordid>eNpdUsFu1DAUjBCIVm1P3JElLltBih174_WlUhqgBC1ltS1ny7FfFq8SuzgJUvkUvhanu1Qtvth-njeaeZ4keUXwWUYYf_-lWp9dU8HmOHuWHBLCFynHlDx_dD5ITvp-i6fFMcvYy-SA5jzLuSCHyZ9iA-mFbW0Ya-vSyg0QnBqsd6pFVz50qrW_waD1VEOz6mp9mpYB4s1ZB2hWXFTlKbrWPsA7pNDKD-AGG3tXwW-c7wer0VdvoEWND2jp3Sa9gdDFWhgi9XCHfIPK4gNaRcrY2qOiiRLQqqyOkxeNans42e9HyfdPH2_Kz-ny22VVFstUMz4fUkGxyWmNc25UjQ3PoWGKzikHM49zUaoWmlGmGUT_iohFrZnQihLNm6amgh4l1Y7XeLWVt8F2KtxJr6y8L_iwkSpEHy1IHccGmhBMmWFaG6GAZTxjeWNqnQkSuc53XLdj3YHR0VFQ7RPSpy_O_pAb_0uKxWLO80nMbE8Q_M8R-kF2ttfQtsqBH3uZcU4Ew3mWR-ib_6BbP8bPa-9RnDJO8knR2x1KB9_3AZoHMQTLKUIyRkjuIxTRrx_rf8D-Cwz9C-8owOU</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2777347161</pqid></control><display><type>article</type><title>Age-Bilirubin-International Normalized Ratio (INR)-Creatinine (ABIC) Score, a Potential Prognostic Model for Long-Term Mortality of CAD Patients After PCI</title><source>Open Access: PubMed Central</source><source>Taylor &amp; Francis Open Access</source><source>Publicly Available Content (ProQuest)</source><creator>Wu, Ting-Ting ; Pan, Ying ; Zheng, Ying-Ying ; Yang, Yi ; Hou, Xian-Geng ; Deng, Chang-Jiang ; Ma, Yi-Tong ; Xie, Xiang</creator><creatorcontrib>Wu, Ting-Ting ; Pan, Ying ; Zheng, Ying-Ying ; Yang, Yi ; Hou, Xian-Geng ; Deng, Chang-Jiang ; Ma, Yi-Tong ; Xie, Xiang</creatorcontrib><description>Given that age, international normalized ratio (INR), total bilirubin, and creatinine are reported to be independent risk factors for predicting outcome in patients with coronary artery disease (CAD), it is possible that the age-bilirubin-INR-creatinine (ABIC) score might be a potential prognostic model for patients with CAD. A total of 6046 CAD patients after percutaneous coronary intervention (PCI) from the retrospective cohort study (Identifier: ChiCTR-ORC-16010153) were evaluated finally. The primary outcome long-term mortality and secondary endpoints mainly major adverse cardiovascular and cerebrovascular events (MACCEs) were recorded. Multivariate Cox regression models were used to determine risk factors for mortality and MACCEs. The ABIC score was significantly higher in the death group than in the survival group. After adjusting for other CAD risk factors, the ABIC score was identified to be an independent risk factor for long-term mortality by multivariate Cox analysis. When in the high ABIC group, the incidence of all-cause mortality would increased 1.7 times (adjusted HR=1.729 (1.347-2.218), &lt;0.001), and 1.5 times for cardiac death (adjusted HR=1.482 (1.126-1.951), =0.005). The present study indicated that ABIC score≥7.985 predicts high long-term mortality and cardiac death risk for PCI patients. The ABIC score might be a potential prognostic model for patients with PCI.</description><identifier>ISSN: 1178-7031</identifier><identifier>EISSN: 1178-7031</identifier><identifier>DOI: 10.2147/JIR.S394502</identifier><identifier>PMID: 36726791</identifier><language>eng</language><publisher>New Zealand: Taylor &amp; Francis Ltd</publisher><subject>Age ; age-bilirubin-international normalized ratio -creatinine (abic) score ; Bilirubin ; Biomarkers ; Blood pressure ; Cardiovascular disease ; Coronary artery disease ; Coronary vessels ; Creatinine ; Death ; Diabetes ; Heart ; Heart attacks ; Heart diseases ; Hepatitis ; Hypertension ; Medical prognosis ; Mortality ; Original Research ; prognosis ; Regression analysis ; Risk factors ; Vein &amp; artery diseases</subject><ispartof>Journal of inflammation research, 2023-01, Vol.16, p.333-341</ispartof><rights>2023 Wu et al.</rights><rights>2023. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2023 Wu et al. 2023 Wu et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c475t-930d63b067dab0d76ef4a3537ed5945aab9c434c4e007a198bc49ca31c7ffb393</citedby><cites>FETCH-LOGICAL-c475t-930d63b067dab0d76ef4a3537ed5945aab9c434c4e007a198bc49ca31c7ffb393</cites><orcidid>0000-0002-0632-4626</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2777347161/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2777347161?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,25731,27901,27902,36989,36990,44566,53766,53768,74869</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36726791$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wu, Ting-Ting</creatorcontrib><creatorcontrib>Pan, Ying</creatorcontrib><creatorcontrib>Zheng, Ying-Ying</creatorcontrib><creatorcontrib>Yang, Yi</creatorcontrib><creatorcontrib>Hou, Xian-Geng</creatorcontrib><creatorcontrib>Deng, Chang-Jiang</creatorcontrib><creatorcontrib>Ma, Yi-Tong</creatorcontrib><creatorcontrib>Xie, Xiang</creatorcontrib><title>Age-Bilirubin-International Normalized Ratio (INR)-Creatinine (ABIC) Score, a Potential Prognostic Model for Long-Term Mortality of CAD Patients After PCI</title><title>Journal of inflammation research</title><addtitle>J Inflamm Res</addtitle><description>Given that age, international normalized ratio (INR), total bilirubin, and creatinine are reported to be independent risk factors for predicting outcome in patients with coronary artery disease (CAD), it is possible that the age-bilirubin-INR-creatinine (ABIC) score might be a potential prognostic model for patients with CAD. A total of 6046 CAD patients after percutaneous coronary intervention (PCI) from the retrospective cohort study (Identifier: ChiCTR-ORC-16010153) were evaluated finally. The primary outcome long-term mortality and secondary endpoints mainly major adverse cardiovascular and cerebrovascular events (MACCEs) were recorded. Multivariate Cox regression models were used to determine risk factors for mortality and MACCEs. The ABIC score was significantly higher in the death group than in the survival group. After adjusting for other CAD risk factors, the ABIC score was identified to be an independent risk factor for long-term mortality by multivariate Cox analysis. When in the high ABIC group, the incidence of all-cause mortality would increased 1.7 times (adjusted HR=1.729 (1.347-2.218), &lt;0.001), and 1.5 times for cardiac death (adjusted HR=1.482 (1.126-1.951), =0.005). The present study indicated that ABIC score≥7.985 predicts high long-term mortality and cardiac death risk for PCI patients. The ABIC score might be a potential prognostic model for patients with PCI.</description><subject>Age</subject><subject>age-bilirubin-international normalized ratio -creatinine (abic) score</subject><subject>Bilirubin</subject><subject>Biomarkers</subject><subject>Blood pressure</subject><subject>Cardiovascular disease</subject><subject>Coronary artery disease</subject><subject>Coronary vessels</subject><subject>Creatinine</subject><subject>Death</subject><subject>Diabetes</subject><subject>Heart</subject><subject>Heart attacks</subject><subject>Heart diseases</subject><subject>Hepatitis</subject><subject>Hypertension</subject><subject>Medical prognosis</subject><subject>Mortality</subject><subject>Original Research</subject><subject>prognosis</subject><subject>Regression analysis</subject><subject>Risk factors</subject><subject>Vein &amp; artery diseases</subject><issn>1178-7031</issn><issn>1178-7031</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNpdUsFu1DAUjBCIVm1P3JElLltBih174_WlUhqgBC1ltS1ny7FfFq8SuzgJUvkUvhanu1Qtvth-njeaeZ4keUXwWUYYf_-lWp9dU8HmOHuWHBLCFynHlDx_dD5ITvp-i6fFMcvYy-SA5jzLuSCHyZ9iA-mFbW0Ya-vSyg0QnBqsd6pFVz50qrW_waD1VEOz6mp9mpYB4s1ZB2hWXFTlKbrWPsA7pNDKD-AGG3tXwW-c7wer0VdvoEWND2jp3Sa9gdDFWhgi9XCHfIPK4gNaRcrY2qOiiRLQqqyOkxeNans42e9HyfdPH2_Kz-ny22VVFstUMz4fUkGxyWmNc25UjQ3PoWGKzikHM49zUaoWmlGmGUT_iohFrZnQihLNm6amgh4l1Y7XeLWVt8F2KtxJr6y8L_iwkSpEHy1IHccGmhBMmWFaG6GAZTxjeWNqnQkSuc53XLdj3YHR0VFQ7RPSpy_O_pAb_0uKxWLO80nMbE8Q_M8R-kF2ttfQtsqBH3uZcU4Ew3mWR-ib_6BbP8bPa-9RnDJO8knR2x1KB9_3AZoHMQTLKUIyRkjuIxTRrx_rf8D-Cwz9C-8owOU</recordid><startdate>20230101</startdate><enddate>20230101</enddate><creator>Wu, Ting-Ting</creator><creator>Pan, Ying</creator><creator>Zheng, Ying-Ying</creator><creator>Yang, Yi</creator><creator>Hou, Xian-Geng</creator><creator>Deng, Chang-Jiang</creator><creator>Ma, Yi-Tong</creator><creator>Xie, Xiang</creator><general>Taylor &amp; Francis Ltd</general><general>Dove</general><general>Dove Medical Press</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7XB</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>KB0</scope><scope>LK8</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-0632-4626</orcidid></search><sort><creationdate>20230101</creationdate><title>Age-Bilirubin-International Normalized Ratio (INR)-Creatinine (ABIC) Score, a Potential Prognostic Model for Long-Term Mortality of CAD Patients After PCI</title><author>Wu, Ting-Ting ; Pan, Ying ; Zheng, Ying-Ying ; Yang, Yi ; Hou, Xian-Geng ; Deng, Chang-Jiang ; Ma, Yi-Tong ; Xie, Xiang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c475t-930d63b067dab0d76ef4a3537ed5945aab9c434c4e007a198bc49ca31c7ffb393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Age</topic><topic>age-bilirubin-international normalized ratio -creatinine (abic) score</topic><topic>Bilirubin</topic><topic>Biomarkers</topic><topic>Blood pressure</topic><topic>Cardiovascular disease</topic><topic>Coronary artery disease</topic><topic>Coronary vessels</topic><topic>Creatinine</topic><topic>Death</topic><topic>Diabetes</topic><topic>Heart</topic><topic>Heart attacks</topic><topic>Heart diseases</topic><topic>Hepatitis</topic><topic>Hypertension</topic><topic>Medical prognosis</topic><topic>Mortality</topic><topic>Original Research</topic><topic>prognosis</topic><topic>Regression analysis</topic><topic>Risk factors</topic><topic>Vein &amp; artery diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wu, Ting-Ting</creatorcontrib><creatorcontrib>Pan, Ying</creatorcontrib><creatorcontrib>Zheng, Ying-Ying</creatorcontrib><creatorcontrib>Yang, Yi</creatorcontrib><creatorcontrib>Hou, Xian-Geng</creatorcontrib><creatorcontrib>Deng, Chang-Jiang</creatorcontrib><creatorcontrib>Ma, Yi-Tong</creatorcontrib><creatorcontrib>Xie, Xiang</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Biological Sciences</collection><collection>ProQuest Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Open Access: DOAJ - Directory of Open Access Journals</collection><jtitle>Journal of inflammation research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wu, Ting-Ting</au><au>Pan, Ying</au><au>Zheng, Ying-Ying</au><au>Yang, Yi</au><au>Hou, Xian-Geng</au><au>Deng, Chang-Jiang</au><au>Ma, Yi-Tong</au><au>Xie, Xiang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Age-Bilirubin-International Normalized Ratio (INR)-Creatinine (ABIC) Score, a Potential Prognostic Model for Long-Term Mortality of CAD Patients After PCI</atitle><jtitle>Journal of inflammation research</jtitle><addtitle>J Inflamm Res</addtitle><date>2023-01-01</date><risdate>2023</risdate><volume>16</volume><spage>333</spage><epage>341</epage><pages>333-341</pages><issn>1178-7031</issn><eissn>1178-7031</eissn><abstract>Given that age, international normalized ratio (INR), total bilirubin, and creatinine are reported to be independent risk factors for predicting outcome in patients with coronary artery disease (CAD), it is possible that the age-bilirubin-INR-creatinine (ABIC) score might be a potential prognostic model for patients with CAD. A total of 6046 CAD patients after percutaneous coronary intervention (PCI) from the retrospective cohort study (Identifier: ChiCTR-ORC-16010153) were evaluated finally. The primary outcome long-term mortality and secondary endpoints mainly major adverse cardiovascular and cerebrovascular events (MACCEs) were recorded. Multivariate Cox regression models were used to determine risk factors for mortality and MACCEs. The ABIC score was significantly higher in the death group than in the survival group. After adjusting for other CAD risk factors, the ABIC score was identified to be an independent risk factor for long-term mortality by multivariate Cox analysis. When in the high ABIC group, the incidence of all-cause mortality would increased 1.7 times (adjusted HR=1.729 (1.347-2.218), &lt;0.001), and 1.5 times for cardiac death (adjusted HR=1.482 (1.126-1.951), =0.005). The present study indicated that ABIC score≥7.985 predicts high long-term mortality and cardiac death risk for PCI patients. The ABIC score might be a potential prognostic model for patients with PCI.</abstract><cop>New Zealand</cop><pub>Taylor &amp; Francis Ltd</pub><pmid>36726791</pmid><doi>10.2147/JIR.S394502</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-0632-4626</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1178-7031
ispartof Journal of inflammation research, 2023-01, Vol.16, p.333-341
issn 1178-7031
1178-7031
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_c726ec11034d4ccd9ae427246fdbc291
source Open Access: PubMed Central; Taylor & Francis Open Access; Publicly Available Content (ProQuest)
subjects Age
age-bilirubin-international normalized ratio -creatinine (abic) score
Bilirubin
Biomarkers
Blood pressure
Cardiovascular disease
Coronary artery disease
Coronary vessels
Creatinine
Death
Diabetes
Heart
Heart attacks
Heart diseases
Hepatitis
Hypertension
Medical prognosis
Mortality
Original Research
prognosis
Regression analysis
Risk factors
Vein & artery diseases
title Age-Bilirubin-International Normalized Ratio (INR)-Creatinine (ABIC) Score, a Potential Prognostic Model for Long-Term Mortality of CAD Patients After PCI
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-04T20%3A45%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Age-Bilirubin-International%20Normalized%20Ratio%20(INR)-Creatinine%20(ABIC)%20Score,%20a%20Potential%20Prognostic%20Model%20for%20Long-Term%20Mortality%20of%20CAD%20Patients%20After%20PCI&rft.jtitle=Journal%20of%20inflammation%20research&rft.au=Wu,%20Ting-Ting&rft.date=2023-01-01&rft.volume=16&rft.spage=333&rft.epage=341&rft.pages=333-341&rft.issn=1178-7031&rft.eissn=1178-7031&rft_id=info:doi/10.2147/JIR.S394502&rft_dat=%3Cproquest_doaj_%3E2771940626%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c475t-930d63b067dab0d76ef4a3537ed5945aab9c434c4e007a198bc49ca31c7ffb393%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2777347161&rft_id=info:pmid/36726791&rfr_iscdi=true