Mortality Related Risk Factors in High-Risk Pulmonary Embolism in the ICU

Introduction. We sought to identify possible risk factors associated with mortality in patients with high-risk pulmonary embolism (PE) after intensive care unit (ICU) admission. Patients and Methods. PE patients, diagnosed with computer tomography pulmonary angiography, were included from two ICUs a...

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Bibliographic Details
Published in:Canadian respiratory journal 2016-01, Vol.2016 (2016), p.1-8
Main Authors: Gökmen, Necati, Cömert, Bilgin, Savran, Yusuf, Tokur, Murat Emre, Aydın, Kutlay, Çalışkan, Taner, Ergün, Recai, Ergan, Begüm, Koca, Uğur
Format: Article
Language:English
Subjects:
Aged
Canada
Care and treatment
Catheters
Female
Health risk assessment
Humans
Intensive care
Intensive Care Units - statistics & numerical data
Male
Middle Aged
Mortality
Patient outcomes
Pulmonary embolism
Pulmonary Embolism - mortality
Pulmonary Embolism - therapy
Retrospective Studies
Risk Factors
Thrombolytic Therapy
Turkey - epidemiology
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Summary:Introduction. We sought to identify possible risk factors associated with mortality in patients with high-risk pulmonary embolism (PE) after intensive care unit (ICU) admission. Patients and Methods. PE patients, diagnosed with computer tomography pulmonary angiography, were included from two ICUs and were categorized into groups: group 1 high-risk patients and group 2 intermediate/low-risk patients. Results. Fifty-six patients were included. Of them, 41 (73.2%) were group 1 and 15 (26.7%) were group 2. When compared to group 2, need for vasopressor therapy (0 vs 68.3%; p18 (OR 42.47 95% CI 1.50–1201.1), invasive mechanical ventilation (OR 30.10 95% CI 1.96–463.31), and thrombolytic therapy (OR 0.03 95% CI 0.01–0.98) were found as independent predictors of mortality. Conclusion. In high-risk PE, admission APACHE II score and need for invasive mechanical ventilation may predict death in ICU. Thrombolytic therapy seems to be beneficial in these patients.
ISSN:1198-2241
1916-7245
DOI:10.1155/2016/2432808