Hepatitis C virus infection in nephrology patients

Context: Hepatitis C virus (HCV) infection leads to chronic liver disease, but also to extra-hepatic manifestations. Evidence Acquisitions: Directory of Open Access Journals (DOAJ), Google Scholar, Pubmed (NLM), LISTA (EBSCO) and Web of Science have been searched. Results: Herein, we provide an over...

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Bibliographic Details
Published in:Journal of nephropathology 2013-10, Vol.2 (4), p.217-233
Main Authors: Rostaing, Lionel, Izopet, Jacques, Kamar, Nassim
Format: Article
Language:English
Subjects:
glomerulonephritis
hepatitis c
membranoproliferative glomerulonephritis
renal transplantation
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Summary:Context: Hepatitis C virus (HCV) infection leads to chronic liver disease, but also to extra-hepatic manifestations. Evidence Acquisitions: Directory of Open Access Journals (DOAJ), Google Scholar, Pubmed (NLM), LISTA (EBSCO) and Web of Science have been searched. Results: Herein, we provide an overview of renal diseases related to HCV and their therapies, as well as the treatment options available for HCV (+)/RNA (+) dialysis patients. We will not mention, however, HCV infection-related complications in the post-kidney transplantation setting. Conclusions: Extra-hepatic manifestations of HCV infection include mixed cryoglobulinemia, lymphoproliferative disorders, and renal disease. HCV infection has been reported in association with distinct histological patterns of glomerulonephritis in native kidneys.
ISSN:2251-8363
2251-8819
DOI:10.12860/JNP.2013.36