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HIV and schistosomiasis in rural Zimbabwe: the association of Retinol-binding protein with disease progression, inflammation and mortality
Highlights • RBP is a marker of vitamin-A status and a negative acute-phase protein. • This is the largest study of interactions between schistosomiasis and HIV. • RBP was negatively correlated with markers of HIV progression and inflammation. • RBP was lower in those co-infected with HIV and S. man...
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| Published in: | International journal of infectious diseases 2015-04, Vol.33 (C), p.159-164 |
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| Main Authors: | , , , , , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c521t-14c6d014f5cd6c6b2bac3eeacfc9aa3c8f0557b84441e59ed69ab97286d79d6b3 |
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| cites | cdi_FETCH-LOGICAL-c521t-14c6d014f5cd6c6b2bac3eeacfc9aa3c8f0557b84441e59ed69ab97286d79d6b3 |
| container_end_page | 164 |
| container_issue | C |
| container_start_page | 159 |
| container_title | International journal of infectious diseases |
| container_volume | 33 |
| creator | Kotzé, Sebastian Ranzi Zinyama-Gutsire, Rutendo Kallestrup, Per Benn, Christine Stabell Gomo, Exnevia Gerstoft, Jan van Dam, Govert Mortensen, Ole Hartvig Ullum, Henrik Erikstrup, Christian |
| description | Highlights • RBP is a marker of vitamin-A status and a negative acute-phase protein. • This is the largest study of interactions between schistosomiasis and HIV. • RBP was negatively correlated with markers of HIV progression and inflammation. • RBP was lower in those co-infected with HIV and S. mansoni. • RBP was negatively correlated with schistosomiasis intensity in these individuals. |
| doi_str_mv | 10.1016/j.ijid.2015.01.015 |
| format | article |
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| identifier | ISSN: 1201-9712 |
| ispartof | International journal of infectious diseases, 2015-04, Vol.33 (C), p.159-164 |
| issn | 1201-9712 1878-3511 |
| language | eng |
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| source | BACON - Elsevier - GLOBAL_SCIENCEDIRECT-OPENACCESS; ScienceDirect Journals |
| subjects | Adult Africa Biomarkers - blood Coinfection - diagnosis Coinfection - mortality Cytokines - blood Disease Progression Female HIV HIV Infections - complications HIV Infections - diagnosis HIV Infections - mortality Humans Infectious Disease Inflammation - immunology Inflammation - virology Male Middle Aged mortality Pulmonary/Respiratory Retinol-binding protein Retinol-Binding Proteins, Plasma - analysis Rural Population schistosomiasis Schistosomiasis - complications Schistosomiasis - diagnosis vitamin A Young Adult Zimbabwe - epidemiology |
| title | HIV and schistosomiasis in rural Zimbabwe: the association of Retinol-binding protein with disease progression, inflammation and mortality |
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