Abdominal Muscles and Metabolic Syndrome According to Patient Sex: A Retrospective Cross-Sectional Study

Computed tomography (CT) is a reference method for measuring skeletal muscle mass, and the amount of fat in the skeletal muscle can be calculated based on CT attenuation. This study aimed to comprehensively investigate the effect of muscle quality and quantity on metabolic syndrome (MetS) according...

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Bibliographic Details
Published in:Healthcare (Basel) 2021-09, Vol.9 (9), p.1197
Main Authors: Lee, Tae Young, Jeon, Young-Jee, Kim, Chung Reen, Kang, Byung Ju, Park, Gyung-Min
Format: Article
Language:English
Subjects:
Abdomen
abdominal muscle
Alcohol
attenuation
Biopsy
Blood pressure
Body mass index
Cholesterol
computed tomography
Cross-sectional studies
Exercise
Glucose
Hospitals
Insulin resistance
Laboratories
Lipids
Medical records
Metabolic syndrome
Musculoskeletal system
Obesity
Overweight
Physical fitness
Sarcopenia
sex characteristics
Software
Triglycerides
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Summary:Computed tomography (CT) is a reference method for measuring skeletal muscle mass, and the amount of fat in the skeletal muscle can be calculated based on CT attenuation. This study aimed to comprehensively investigate the effect of muscle quality and quantity on metabolic syndrome (MetS) according to sex. This retrospective cross-sectional study enrolled 8081 individuals aged ≥20 years who underwent self-referral abdominopelvic CT at our hospital. The total abdominal muscle area (TAMA), low-attenuation abdominal muscle area (LAMA), normal-attenuation abdominal muscle area (NAMA), and extramyocellular lipid area (EMCLA) were measured using cross-sectional CT data of the L3 lumbar vertebrae. The TAMA and NAMA showed negative correlations with risk factors for MetS and a positive correlation with high-density lipoprotein cholesterol, whereas the LAMA and EMCLA showed an inverse trend in both the sexes (p < 0.001). After adjusting for various factors, a higher LAMA index and the ratio of LAMA to TAMA were associated with a higher prevalence of MetS. High TAMA indices were associated with a lower prevalence of MetS. Furthermore, muscle quality and quantity were associated with the prevalence of MetS in both males and females. However, the LAMA showed a stronger association with MetS in males than in females.
ISSN:2227-9032
2227-9032
DOI:10.3390/healthcare9091197