A Review of the Potential Health Benefits of Nigella sativa on Obesity and Its Associated Complications

Obesity has become a worldwide epidemic and its prevalence continues to increase at an alarming rate. It is considered a major risk factor for the development of several comorbidities, including type 2 diabetes, stroke, other cardiovascular diseases and even cancer. Conventional treatments for obesi...

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Bibliographic Details
Published in:Plants (Basel) 2023-09, Vol.12 (18), p.3210
Main Authors: Adam, Siti Hajar, Abu, Izuddin Fahmy, Kamal, Datu Agasi Mohd, Febriza, Ami, Kashim, Mohd Izhar Ariff Mohd, Mokhtar, Mohd Helmy
Format: Article
Language:English
Subjects:
anti-obesity
antioxidants
Apoptosis
body weight
Cancer therapies
Cardiovascular diseases
Chemical compounds
Comorbidity
Diabetes
Diabetes mellitus (non-insulin dependent)
Drug therapy
Fatty acids
Herbal medicine
Medicinal plants
Medicine
Metabolism
Natural products
Nigella sativa
Obesity
Overweight
Phytochemicals
Polyphenols
Review
Risk factors
Seeds
Side effects
thymoquinone
Weight control
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Summary:Obesity has become a worldwide epidemic and its prevalence continues to increase at an alarming rate. It is considered a major risk factor for the development of several comorbidities, including type 2 diabetes, stroke, other cardiovascular diseases and even cancer. Conventional treatments for obesity, such as dietary interventions, exercise and pharmacotherapy, have proven to have limited effectiveness and are often associated with undesirable side effects. Therefore, there is a growing interest in exploring alternative therapeutic approaches. Nigella sativa (NS), a medicinal plant with multiple pharmacological properties, has gained attention due to its potential role in the treatment of obesity and its associated complications. The aim of this review is therefore to assess the effects of NS on obesity and its complications and to provide insights into the underlying mechanisms. From this review, NS appears to play a complementary or supportive role in the treatment of obesity and its complications. However, future studies are needed to verify the efficacy of NS in the treatment of obesity and its complications and to prove its safety so that it can be introduced in patients with obesity.
ISSN:2223-7747
2223-7747
DOI:10.3390/plants12183210