Encapsulation for Cancer Therapy

The current rapid advancement of numerous nanotechnology tools is being employed in treatment of many terminal diseases such as cancer. Nanocapsules (NCs) containing an anti-cancer drug offer a very promising alternative to conventional treatments, mostly due to their targeted delivery and precise a...

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2020-03, Vol.25 (7), p.1605
Main Authors: Montané, Xavier, Bajek, Anna, Roszkowski, Krzysztof, Montornés, Josep M, Giamberini, Marta, Roszkowski, Szymon, Kowalczyk, Oliwia, Garcia-Valls, Ricard, Tylkowski, Bartosz
Format: Article
Language:English
Subjects:
Animals
anticancer therapy
Antineoplastic Agents - chemistry
Antineoplastic Agents - pharmacology
Biopolymers - chemistry
Biosensors
Cancer
Cancer therapies
Dendrimers
Drug Carriers - chemistry
Drug Compounding
Drug delivery
Drug Delivery Systems
Encapsulation
Gold
Humans
Liposomes
Medical imaging
Medical treatment
Micelles
nanocapsules (NCs)
Nanocapsules - chemistry
Nanocapsules - ultrastructure
Nanomaterials
nanomedicine
Nanoparticles
Nanoparticles - chemistry
Nanoparticles - ultrastructure
Nanotechnology
Quantum dots
Review
Theranostic Nanomedicine
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Summary:The current rapid advancement of numerous nanotechnology tools is being employed in treatment of many terminal diseases such as cancer. Nanocapsules (NCs) containing an anti-cancer drug offer a very promising alternative to conventional treatments, mostly due to their targeted delivery and precise action, and thereby they can be used in distinct applications: as biosensors or in medical imaging, allowing for cancer detection as well as agents/carriers in targeted drug delivery. The possibility of using different systems-inorganic nanoparticles, dendrimers, proteins, polymeric micelles, liposomes, carbon nanotubes (CNTs), quantum dots (QDs), biopolymeric nanoparticles and their combinations-offers multiple benefits to early cancer detection as well as controlled drug delivery to specific locations. This review focused on the key and recent progress in the encapsulation of anticancer drugs that include methods of preparation, drug loading and drug release mechanism on the presented nanosystems. Furthermore, the future directions in applications of various nanoparticles are highlighted.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules25071605