The Association between Dietary Antioxidant Indices and Cardiac Disease: Baseline Data of Kharameh Cohort Study

• Published in: Journal of biostatistics and epidemiology 2022-12, Vol.8 (4)
• Main Authors: Keshani, Parisa, Jalali, Maryam, Johari, Masoumeh Ghoddusi, Rezaeianzadeh, Ramin, Hosseini, Seyed Vahid, Rezaianzadeh, Abbas
• Format: Article
• Language: English
• Subjects: Cardiac disease; Dietary antioxidant index; Dietary antioxidant quality; Dietary intake; Keywords: Antioxidants
• ISSN: 2383-4196; 2383-420X
• DOI: 10.18502/jbe.v8i4.13358

Introduction: Oxidative stress contributes to the development of cardiovascular disease. Tools for evaluating the anti-inflammatory and antioxidative characteristics of an individual’s diet as a whole may be valuable for assessing the combined effects of dietary antioxidants on health. This population-based study aimed to investigate the association between dietary antioxidants and cardiac disease. Methods: In this population-based cross-sectional study, 10439 individuals aged 40-70 years were recruited during 2014-2017 in Kherameh cohort study which is a part of the Prospective Epidemiological Research Studies in Iran (PERSIAN). The food frequency questionnaire (FFQ) with 130 food items was used to assess the dietary intakes. Vitamin A, E, C, selenium, zinc and Manganese intakes were used to compute dietary antioxidant index (DAI) and dietary antioxidant quality score (DAQs). Chi-square and independent sample T-test was used for comparing qualitative and quantitative variables between the groups respectively Logistic regression analysis was applied for evaluating the association between cardiac disease, DAI and DAQS score after adjusting for covariates. Results: The participants’ mean age was 52.1±8.3 years. Among all, 4356 (41.7%) were overweight and 1892 (18.1%) were obese. According to the results, odds of cardiac diseases decreased by increasing DAI score (OR=0.80, P value