An Appraisal of the Current Scenario in Vaccine Research for COVID-19

The recent coronavirus disease 2019 (COVID-19) outbreak has drawn global attention, affecting millions, disrupting economies and healthcare modalities. With its high infection rate, COVID-19 has caused a colossal health crisis worldwide. While information on the comprehensive nature of this infectio...

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Bibliographic Details
Published in:Viruses 2021-07, Vol.13 (7), p.1397
Main Authors: Chong, Wai Chin, Chellappan, Dinesh K, Shukla, Shakti D, Peterson, Gregory M, Patel, Rahul P, Jha, Niraj Kumar, Eri, Rajaraman D, Dua, Kamal, Tambuwala, Murtaza M, Shastri, Madhur D
Format: Article
Language:English
Subjects:
Antigens
Coronaviruses
COVID-19
COVID-19 - epidemiology
COVID-19 - immunology
COVID-19 - prevention & control
COVID-19 - virology
COVID-19 vaccines
COVID-19 Vaccines - immunology
Disease transmission
Epidemics
Genomics
Herd immunity
Humans
Immunity
Immunity, Herd
Infectious diseases
Pandemics
Pathogens
Proteins
Public health
R&D
Research & development
Respiratory diseases
Review
SARS-CoV-2
SARS-CoV-2 - isolation & purification
Severe acute respiratory syndrome coronavirus 2
Therapeutic targets
Vaccination
Vaccines
Vectors (Biology)
Viruses
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Summary:The recent coronavirus disease 2019 (COVID-19) outbreak has drawn global attention, affecting millions, disrupting economies and healthcare modalities. With its high infection rate, COVID-19 has caused a colossal health crisis worldwide. While information on the comprehensive nature of this infectious agent, SARS-CoV-2, still remains obscure, ongoing genomic studies have been successful in identifying its genomic sequence and the presenting antigen. These may serve as promising, potential therapeutic targets in the effective management of COVID-19. In an attempt to establish herd immunity, massive efforts have been directed and driven toward developing vaccines against the SARS-CoV-2 pathogen. This review, in this direction, is aimed at providing the current scenario and future perspectives in the development of vaccines against SARS-CoV-2.
ISSN:1999-4915
1999-4915
DOI:10.3390/v13071397