Longitudinal study of disease severity and external factors in cognitive failure after COVID-19 among Indonesian population

• Published in: Scientific reports 2023-11, Vol.13 (1), p.19405-19405, Article 19405
• Main Authors: Herman, Bumi, Wong, Martin Chi Sang, Chantharit, Prawat, Hannanu, Firdaus Fabrice, Viwattanakulvanid, Pramon
• Format: Article
• Language: English
• Subjects: 631/378; 692/617; 692/699; 692/699/255; 692/700; Anxiety; Anxiety disorders; Cognition; Cognitive ability; Comorbidity; COVID-19; COVID-19 - complications; COVID-19 - epidemiology; COVID-19 vaccines; Failure; Fatigue; Fatigue - epidemiology; Fatigue - etiology; Humanities and Social Sciences; Humans; Immunization; Indonesia - epidemiology; Longitudinal Studies; multidisciplinary; NCT; NCT05060562; Patient Acuity; Science; Science (multidisciplinary); Vaccination
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-023-46334-2

The COVID-19 infection is assumed to induce cognitive failure. Identifying the relationship between COVID-19, the effect of vaccination and medication, and accommodating non-COVID-19 factors to cognitive failure is essential. This study was conducted in Indonesia from September 2021 to January 2023. Demographic information, clinical data, comorbidities, vaccination, and medication during COVID-19 were obtained, as well as a 6-month cognitive assessment with Cognitive Failures Questionnaire/CFQ, Fatigue Severity Score, and Generalized Anxiety Disorder (GAD-7). A Structural Equation Model explains the relationship between potential predictors and cognitive failure. The average score of CFQ after 6 months was 45.6 ± 23.1 out of 100. The severity of the disease, which was associated with vaccination status, age, previous infection, and unit of treatment ( p