CircRNA expression profiles and circRNA-miRNA-mRNA crosstalk in allergic rhinitis

Circular RNAs (circRNAs) are involved in inflammation; however, their role in allergic rhinitis (AR) remains unclear. In this study, we analyzed circRNA expression and identified a circRNA-miRNA-mRNA network through which circRNAs regulate AR pathogenesis. We analyzed circRNA, miRNA, and mRNA expres...

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Bibliographic Details
Published in:The World Allergy Organization journal 2021-06, Vol.14 (6), p.100548-100548, Article 100548
Main Authors: Qiu, Chang-Yu, Cui, Xin-Yan, Lu, Mei-Ping, Yin, Min, Xu, Wan-Yun, Zhu, Xin-Jie, Yang, Qing, Cheng, Lei
Format: Article
Language:English
Subjects:
Allergic rhinitis
Allergies
Circular RNA
Genes
Hay fever
microRNA
MicroRNAs
mRNA
Nasal mucosa
Rhinitis
Software
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Summary:Circular RNAs (circRNAs) are involved in inflammation; however, their role in allergic rhinitis (AR) remains unclear. In this study, we analyzed circRNA expression and identified a circRNA-miRNA-mRNA network through which circRNAs regulate AR pathogenesis. We analyzed circRNA, miRNA, and mRNA expression profiles in the nasal mucosa by high-throughput sequencing (HTS), using a fold-change >1.5 and p-value 
ISSN:1939-4551
1939-4551
DOI:10.1016/j.waojou.2021.100548