Six-minute walk test may be a reliable predictor of peak oxygen uptake in patients undergoing hemodialysis

BackgroundCardiorespiratory fitness seems to play an important role in the general health of patients undergoing hemodialysis (HD). However, the prediction of peak oxygen uptake (V̇O2peak) in a clinical setting is not widely adopted for these patients.ObjectivesEvaluate the agreement and reliability...

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Published in:Renal replacement therapy 2023-01, Vol.9 (1), p.6-7, Article 6
Main Authors: Andrade, Francini Porcher, Ribeiro, Heitor Siqueira, Benvenutti, Heloíse, de Oliveira, Samantha Gonçalves, Thomé, Fernando Saldanha, Veronese, Francisco Veríssimo, Rovedder, Paula Maria Eidt
Format: Article
Language:English
Subjects:
Blood pressure
Cardiopulmonary exercise test
Cardiovascular disease
Chronic kidney disease
Dyspnea
Exercise
Fatigue
Fistula
Hemodialysis
Kidney diseases
Maximum oxygen consumption
Oxygen uptake
Patients
Physical fitness
Physical fitness tests
Pulse oximetry
Six-minute walk test
Statistical analysis
Walking
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Summary:BackgroundCardiorespiratory fitness seems to play an important role in the general health of patients undergoing hemodialysis (HD). However, the prediction of peak oxygen uptake (V̇O2peak) in a clinical setting is not widely adopted for these patients.ObjectivesEvaluate the agreement and reliability between directly and indirectly V̇O2peak measurements in patients undergoing HD. MethodsThis is a cross-sectional study with patients undergoing HD that performed a cardiopulmonary exercise test (CPET) with 5/10 watts incremental load in each minute using a cycle ergometry to directly evaluate the V̇O2peak, and the 6-min walk test (6MWT) in a 30-m corridor to indirect measures it. Both tests were performed on a midweek non-dialysis day. Bland–Altman analysis of agreement limits was used with direct and indirect V̇O2peak values. Intraclass correlation coefficient (ICC) and Cronbach’s Alpha was used to evaluate the reproducibility and reliability between direct and indirect V̇O2peak values.ResultsTwenty-six patients (54.4 ± 14.5 years, 53.8% of male) were evaluated. The V̇O2peak direct mean obtained through CPET was 15.91 ± 5.26 (ml/kg/min), while the indirect mean obtained through 6MWT was V̇O2peak of 14.89 ± 4.21 (ml/kg/min). There was a strong positive correlation between both V̇O2peak values (r = 0.734; p 
ISSN:2059-1381
2059-1381
DOI:10.1186/s41100-023-00460-9