Real-time prediction of bladder urine leakage using fuzzy inference system and dual Kalman filtering in cats

The use of electrical stimulation devices to manage bladder incontinence relies on the application of continuous inhibitory stimulation. However, continuous stimulation can result in tissue fatigue and increased delivered charge. Here, we employ a real-time algorithm to provide a short-time predicti...

Full description

Saved in:
Bibliographic Details
Published in:Scientific reports 2024-02, Vol.14 (1), p.3879-3879, Article 3879
Main Authors: Qasemi, Amirhossein, Aminian, Alireza, Erfanian, Abbas
Format: Article
Language:English
Subjects:
631/553/1806
639/166/985
Animals
Bladder
Cats
Electric Stimulation Therapy - methods
Electrical stimuli
Humanities and Social Sciences
Leakage
multidisciplinary
Prosthetics
Science
Science (multidisciplinary)
Urinary Bladder - physiology
Urinary Bladder, Overactive - therapy
Urinary Incontinence
Urination - physiology
Urine
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The use of electrical stimulation devices to manage bladder incontinence relies on the application of continuous inhibitory stimulation. However, continuous stimulation can result in tissue fatigue and increased delivered charge. Here, we employ a real-time algorithm to provide a short-time prediction of urine leakage using the high-resolution power spectrum of the bladder pressure during the presence of non-voiding contractions (NVC) in normal and overactive bladder (OAB) cats. The proposed method is threshold-free and does not require pre-training. The analysis revealed that there is a significant difference between voiding contraction (VC) and NVC pressures as well as band powers (0.5–5 Hz) during both normal and OAB conditions. Also, most of the first leakage points occurred after the maximum VC pressure, while all of them were observed subsequent to the maximum VC spectral power. Kalman-Fuzzy method predicted urine leakage on average 2.2 s and 1.6 s before its occurrence and an average of 2.0 s and 1.1 s after the contraction started with success rates of 94.2% and 100% in normal and OAB cats, respectively. This work presents a promising approach for developing a neuroprosthesis device, with on-demand stimulation to control bladder incontinence.
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-024-53629-5