Agreement of Tear Break-Up Time and Meniscus Height between Medmont E300 and Visionix VX120

• Published in: Applied sciences 2022-05, Vol.12 (9), p.4589
• Main Authors: Martínez-Plaza, Elena, Molina-Martín, Ainhoa, Piñero, David P.
• Format: Article
• Language: English
• Subjects: agreement; Agreements; Cornea; Evaluation; interchangeability; NIBUT; non-invasive tear break-up time; Regression analysis; Statistical analysis; tear meniscus height; TMH; Topography; Values
• ISSN: 2076-3417; 2076-3417
• DOI: 10.3390/app12094589

The goal of this study was to analyze the agreement between the Medmont E300 and the Visionix VX120+ systems in terms of non-invasive tear break-up time (NIBUT) and tear meniscus height (TMH) measurements. A total of 60 eyes (30 healthy subjects) were enrolled. NIBUT and TMH were evaluated with Medmont E300; first NIBUT, NIBUT50%, and TMH were evaluated with Visionix VX120+. Both evaluations were performed in a random order by the same clinician for right, left, and both eyes. The Medmont E300 provided significantly higher NIBUT than Visionix VX120+ for first NIBUT in right, left, and both eyes (p ≤ 0.003) and NIBUT50% in left and both eyes (p ≤ 0.042). The TMH measured with VX120+ was significantly higher than with Medmont E300 considering both eyes (p = 0.037). No significant correlations were found between both devices for either NIBUT (p ≥ 0.11) or TMH (p ≥ 0.09). Passing–Bablok regression analyses revealed poor agreement between devices for NIBUT and TMH outcomes. VX120+ is expected to provide substantial lower first NIBUT values than the NIBUT measured by Medmont E300. Clinicians should consider not using both instruments as interchangeable for dry eye diagnosis.