Health-related quality of life among thalassemia patients in Bangladesh using the SF-36 questionnaire

Thalassemia is one of the most common autosomal recessive hereditary blood disorders worldwide, especially in developing countries, including Bangladesh. Thus, this study aimed to determine HRQoL and its determinants of thalassemia patients (TP) in Bangladesh. A cross-sectional survey was performed...

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Bibliographic Details
Published in:Scientific reports 2023-05, Vol.13 (1), p.7734-7734, Article 7734
Main Authors: Hossain, Md Jubayer, Islam, Md Wahidul, Munni, Ummi Rukaiya, Gulshan, Rubaiya, Mukta, Sumaiya Akter, Miah, Md Sharif, Sultana, Sabia, Karmakar, Mousumi, Ferdous, Jannatul, Islam, Mohammad Ariful
Format: Article
Language:English
Subjects:
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Adult
Bangladesh - epidemiology
Blood diseases
Blood transfusion
Blood transfusions
Comorbidity
Cross-Sectional Studies
Developing countries
Female
Females
Hematological diseases
Humanities and Social Sciences
Humans
Income
LDCs
Male
multidisciplinary
Quality of Life
Science
Science (multidisciplinary)
Statistical analysis
Surveys and Questionnaires
Thalassemia
Thalassemia - epidemiology
Thalassemia - therapy
Transfusion
Variance analysis
Young Adult
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Summary:Thalassemia is one of the most common autosomal recessive hereditary blood disorders worldwide, especially in developing countries, including Bangladesh. Thus, this study aimed to determine HRQoL and its determinants of thalassemia patients (TP) in Bangladesh. A cross-sectional survey was performed on 356 randomly selected thalassemia patients. Participants were invited to face-to-face interviews. Descriptive statistics (frequencies and percentages), independent t-test, ANOVA, and multivariate (linear and logistic regression) analysis was performed to analyze the data. Our demographic data showed that among 356 patients, 54% and 46% were male and female, respectively, with an average age of 19.75 (SD = 8.02) years. Most were transfusion-dependent (91%), 26% had comorbidities, and 52% were from low-income families. In the case of HRQoL, male patients showed significantly higher scores of bodily pains and physical health summaries than female patients. Lower income, high blood transfusion status, disease severity, comorbidities, and medical expenses ( p  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-023-34205-9