Emergence of High Prevalence of Extended-Spectrum Beta-Lactamase and Carbapenemase Producing Acinetobacter Species and Pseudomonas aeruginosa Among Hospitalized Patients at Dessie Comprehensive Specialized Hospital, North-East Ethiopia

The emergence of extended spectrum beta lactamase and carbapenemase production of and is a great concern and major cause of nosocomial infections due to its ability to production of extended spectrum beta lactamase and carbapenemase enzymes. To assess Emergence of high prevalence of extended-spectru...

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Bibliographic Details
Published in:Infection and drug resistance 2022-01, Vol.15, p.895-911
Main Authors: Tilahun, Mihret, Gedefie, Alemu, Bisetegn, Habitye, Debash, Habtu
Format: Article
Language:English
Subjects:
Acinetobacter
Agar
Amikacin
Antibiotics
Antimicrobial agents
Aztreonam
Bacterial infections
Beta lactamases
Carbapenemase
Data collection
Drug resistance
Drug resistance in microorganisms
extended-spectrum beta-lactamase
Health aspects
Hospital patients
Hospitals
Infection
Intensive care
Lactose
Multidrug resistance
Nosocomial infection
Nosocomial infections
Original Research
Patients
Pediatrics
Piperacillin
Pseudomonas aeruginosa
Social aspects
Species
Statistical analysis
Tazobactam
Urinary tract diseases
Urinary tract infections
Urine
Urogenital system
Wound infection
β Lactamase
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Summary:The emergence of extended spectrum beta lactamase and carbapenemase production of and is a great concern and major cause of nosocomial infections due to its ability to production of extended spectrum beta lactamase and carbapenemase enzymes. To assess Emergence of high prevalence of extended-spectrum beta-lactamase and Carbapenemase producing species and among hospitalized patients at Dessie Comprehensive Specialized Hospital, North-East Ethiopia. A hospital-based cross-sectional study was conducted from February-August 2021 at Dessie Referral Hospital in the North eastern Ethiopia. A total of 423 clinical samples taken from admitted patients. Clinical specimens were collected aseptically and inoculated on blood agar and MacConkey agar media. Antimicrobial susceptibility test, ESBL and carbapenemase production were performed as CLSI guideline. The data were entered into the Epi-data and imported to Statistical Package for Social Science version 25. P value of
ISSN:1178-6973
1178-6973
DOI:10.2147/IDR.S358116