Functional and structural evaluation in the lungs of children with repaired congenital diaphragmatic hernia

To evaluate the long-term functional and structural pulmonary development in children with repaired congenital diaphragmatic hernia (CDH) and to identify the associated perinatal-neonatal risk factors. Children with repaired CDH through corrective surgery who were born at gestational age ≥ 35 weeks...

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Bibliographic Details
Published in:BMC pediatrics 2021-03, Vol.21 (1), p.120-120, Article 120
Main Authors: Koh, June-Young, Jung, Euiseok, Goo, Hyun Woo, Kim, Seong-Chul, Kim, Dae Yeon, Namgoong, Jung-Man, Lee, Byong Sop, Kim, Ki-Soo, Kim, Ellen Ai-Rhan
Format: Article
Language:English
Subjects:
Abdomen
Birth defects
Birth weight
Care and treatment
Computed tomography
Congenital diaphragmatic hernia
Congenital diseases
Diaphragm
Gestational age
Hernia
Hernias
Intensive care
Lungs
Medical imaging
Multivariate analysis
Pediatric research
Pediatrics
Physiological aspects
Pulmonary function tests
Pulmonary hypertension
Respiratory physiology
Risk factors
Statistical analysis
Surgery
Ventilators
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Summary:To evaluate the long-term functional and structural pulmonary development in children with repaired congenital diaphragmatic hernia (CDH) and to identify the associated perinatal-neonatal risk factors. Children with repaired CDH through corrective surgery who were born at gestational age ≥ 35 weeks were included in this analysis. Those who were followed for at least 5 years were subjected to spirometry and chest computed tomography for evaluation of their functional and structural growth. Main bronchus diameters and lung volumes (total, left/right) were measured. According to total lung volume (TLV) relative to body surface area, children were grouped into TLV ≥ 50 group and TLV 
ISSN:1471-2431
1471-2431
DOI:10.1186/s12887-021-02586-3