Time to pregnancy in women with previous ectopic pregnancy undergoing in vitro fertilization treatment: a retrospective cohort study

We aimed to investigate the difference in the time to pregnancy (TTP) between women with previous ectopic pregnancy (EP) and control women following in vitro fertilization (IVF) treatment and the association between TTP and the number of oocytes retrieved and embryos available. A retrospective study...

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Published in:Scientific reports 2022-05, Vol.12 (1), p.8820-8820, Article 8820
Main Authors: Xue, Yamei, Zhang, Fuxing, Zhang, Haocheng, Zhang, Songying
Format: Article
Language:English
Subjects:
692/699/2732
692/699/2732/1577
Abortion
Cohort analysis
Ectopic pregnancy
Embryos
Female
Fertilization in Vitro
Humanities and Social Sciences
Humans
In vitro fertilization
multidisciplinary
Oocytes
Pregnancy
Pregnancy complications
Pregnancy Rate
Pregnancy, Ectopic
Retrospective Studies
Science
Science (multidisciplinary)
Time-to-Pregnancy
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Zhang, Haocheng
Zhang, Songying
description We aimed to investigate the difference in the time to pregnancy (TTP) between women with previous ectopic pregnancy (EP) and control women following in vitro fertilization (IVF) treatment and the association between TTP and the number of oocytes retrieved and embryos available. A retrospective study involving 1097 women, 547 of which had previous EP and 550 were control women whose previous pregnancy were abortion, was conducted. Women in the EP group had significantly longer median TTP than those in the control group (36; range, 12–252 vs 28; range, 12–220; P = 0.019). For women with previous EP, > 48 months TTP was most likely associated with low numbers of oocytes retrieved and embryos available compared to TTP of ≤ 24 months or 25–48 months, and women with younger age had a shorter TTP, higher numbers of oocytes retrieved and embryos available. A Cox proportional hazards model showed that maternal age was significantly related to the pregnancy over the TTP (adjusted hazard ratio, 0.934; P 
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A retrospective study involving 1097 women, 547 of which had previous EP and 550 were control women whose previous pregnancy were abortion, was conducted. Women in the EP group had significantly longer median TTP than those in the control group (36; range, 12–252 vs 28; range, 12–220; P = 0.019). For women with previous EP, &gt; 48 months TTP was most likely associated with low numbers of oocytes retrieved and embryos available compared to TTP of ≤ 24 months or 25–48 months, and women with younger age had a shorter TTP, higher numbers of oocytes retrieved and embryos available. A Cox proportional hazards model showed that maternal age was significantly related to the pregnancy over the TTP (adjusted hazard ratio, 0.934; P &lt; 0.001). In conclusion, women with previous EP have a significantly increased TTP than control women with previous abortion. 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subjects 692/699/2732
692/699/2732/1577
Abortion
Cohort analysis
Ectopic pregnancy
Embryos
Female
Fertilization in Vitro
Humanities and Social Sciences
Humans
In vitro fertilization
multidisciplinary
Oocytes
Pregnancy
Pregnancy complications
Pregnancy Rate
Pregnancy, Ectopic
Retrospective Studies
Science
Science (multidisciplinary)
Time-to-Pregnancy
title Time to pregnancy in women with previous ectopic pregnancy undergoing in vitro fertilization treatment: a retrospective cohort study
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