Improved Outcomes in Eosinophilic Esophagitis with Higher Medication Possession Ratio

Eosinophilic esophagitis (EoE) disease activity can be caused by treatment non-adherence. Medication possession ratio (MPR) is an established metric of medication adherence. A higher MPR correlates with better outcomes in several chronic diseases, but MPR has not been investigated with respect to Eo...

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Bibliographic Details
Published in:Medicines (Basel, Switzerland) Switzerland), 2024-03, Vol.11 (4), p.8
Main Authors: Kolasinski, Nathan T, Pasman, Eric A, Nylund, Cade M, Reeves, Patrick T, Brooks, Daniel I, Lescouflair, Katerina G, Min, Steve B
Format: Article
Language:English
Subjects:
adherence
Adults
Biopsy
Chronic illnesses
Combination therapy
compliance
cost
Disease
Drug therapy
Dysphagia
Eosinophilia
eosinophilic esophagitis
Esophagitis
Esophagus
Evaluation
FDA approval
Medical records
medication possession ratio
Patient compliance
Patient outcomes
Patients
Pharmacy
Remission (Medicine)
safety
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Summary:Eosinophilic esophagitis (EoE) disease activity can be caused by treatment non-adherence. Medication possession ratio (MPR) is an established metric of medication adherence. A higher MPR correlates with better outcomes in several chronic diseases, but MPR has not been investigated with respect to EoE. A retrospective cohort study was performed using an established EoE registry for the years 2005 to 2020. Treatment periods were identified, MPRs were calculated, and medical records were assessed for histologic remission (
ISSN:2305-6320
2305-6320
DOI:10.3390/medicines11040008