Severe cutaneous thrombosis with hemorrhagic necrosis in a patient with paroxysmal nocturnal hemoglobinuria: A case report and review of literature

Abstract Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, chronic acquired clonal stem cell disorder, typically manifesting hemolysis, pancytopenia and thrombosis in various organs. PNH-associated cutaneous thrombosis is extremely rare. Herein, we report a case of severe cutaneous thrombosis wit...

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Bibliographic Details
Published in:Zhonghua pi fu ke yi xue za zhi 2017-09, Vol.35 (3), p.138-141
Main Authors: Hsieh, Fu-Nien, Chen, Tsai-Yun, Lee, Julia Yu-Yun
Format: Article
Language:English
Subjects:
Dermatology
neutrophilic infiltrate
Paroxysmal nocturnal hemoglobinuria
thrombosis
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Summary:Abstract Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, chronic acquired clonal stem cell disorder, typically manifesting hemolysis, pancytopenia and thrombosis in various organs. PNH-associated cutaneous thrombosis is extremely rare. Herein, we report a case of severe cutaneous thrombosis with hemorrhagic necrosis in a patient with PNH and review the literature.
ISSN:1027-8117
DOI:10.1016/j.dsi.2017.01.006