Disposable Pencil Graphite Electrode for Diosmin Voltammetric Analysis

Diosmin (DIO) is a naturally occurring flavonoid with multiple beneficial effects on human health. The presence of different hydroxyl groups in diosmin structure enables its electrochemical investigation and quantification. This work presents, for the first time, diosmin voltammetric behavior and qu...

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Bibliographic Details
Published in:Micromachines (Basel) 2021-03, Vol.12 (4), p.351
Main Authors: David, Iulia Gabriela, Oancea, Alexandra-Gabriela, Buleandră, Mihaela, Popa, Dana Elena, Iorgulescu, Emilia Elena, Ciobanu, Adela Magdalena
Format: Article
Language:English
Subjects:
adsorptive stripping voltammetry
Adsorptivity
Alzheimer's disease
Carbon
cyclic voltammetry
Dietary supplements
differential pulse voltammetry
diosmin
disposable working electrode
Electrodes
Electrolytes
Graphite
Hydroxyl groups
Investigations
Memory
Oxidation
pencil graphite electrode
Reagents
Sulfuric acid
Tumor necrosis factor-TNF
Voltammetry
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Summary:Diosmin (DIO) is a naturally occurring flavonoid with multiple beneficial effects on human health. The presence of different hydroxyl groups in diosmin structure enables its electrochemical investigation and quantification. This work presents, for the first time, diosmin voltammetric behavior and quantification on the cost-effective, disposable pencil graphite electrode (PGE). Diosmin oxidation on PGE involves two irreversible steps, generating products with reversible redox behaviors. All electrode processes are pH-dependent and predominantly adsorption-controlled. Differential pulse (DPV) and adsorptive stripping differential pulse (AdSDPV) voltammetric methods have been optimized for diosmin quantification o an H-type PGE, in 0.100 mol/L H SO . The linear ranges and limits of detection were for DPV 1.00 × 10 -1.00 × 10 mol/L and 2.76 × 10 mol/L DIO for DPV and 1.00 × 10 -2.50 × 10 mol/L and 7.42 × 10 mol/L DIO for AdSDPV, respectively. The DPV method was successfully applied for diosmin quantification in dietary supplement tablets. The percentage recovery was 99.87 ± 4.88%.
ISSN:2072-666X
2072-666X
DOI:10.3390/mi12040351