Loading…

Disposable Pencil Graphite Electrode for Diosmin Voltammetric Analysis

Diosmin (DIO) is a naturally occurring flavonoid with multiple beneficial effects on human health. The presence of different hydroxyl groups in diosmin structure enables its electrochemical investigation and quantification. This work presents, for the first time, diosmin voltammetric behavior and qu...

Full description

Saved in:
Bibliographic Details
Published in:Micromachines (Basel) 2021-03, Vol.12 (4), p.351
Main Authors: David, Iulia Gabriela, Oancea, Alexandra-Gabriela, Buleandră, Mihaela, Popa, Dana Elena, Iorgulescu, Emilia Elena, Ciobanu, Adela Magdalena
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c472t-3ffa85edc9fb61269cb7cff80dab0eb65b1144dd0f8a5332bd4180137ce8d7ee3
cites cdi_FETCH-LOGICAL-c472t-3ffa85edc9fb61269cb7cff80dab0eb65b1144dd0f8a5332bd4180137ce8d7ee3
container_end_page
container_issue 4
container_start_page 351
container_title Micromachines (Basel)
container_volume 12
creator David, Iulia Gabriela
Oancea, Alexandra-Gabriela
Buleandră, Mihaela
Popa, Dana Elena
Iorgulescu, Emilia Elena
Ciobanu, Adela Magdalena
description Diosmin (DIO) is a naturally occurring flavonoid with multiple beneficial effects on human health. The presence of different hydroxyl groups in diosmin structure enables its electrochemical investigation and quantification. This work presents, for the first time, diosmin voltammetric behavior and quantification on the cost-effective, disposable pencil graphite electrode (PGE). Diosmin oxidation on PGE involves two irreversible steps, generating products with reversible redox behaviors. All electrode processes are pH-dependent and predominantly adsorption-controlled. Differential pulse (DPV) and adsorptive stripping differential pulse (AdSDPV) voltammetric methods have been optimized for diosmin quantification o an H-type PGE, in 0.100 mol/L H SO . The linear ranges and limits of detection were for DPV 1.00 × 10 -1.00 × 10 mol/L and 2.76 × 10 mol/L DIO for DPV and 1.00 × 10 -2.50 × 10 mol/L and 7.42 × 10 mol/L DIO for AdSDPV, respectively. The DPV method was successfully applied for diosmin quantification in dietary supplement tablets. The percentage recovery was 99.87 ± 4.88%.
doi_str_mv 10.3390/mi12040351
format article
fullrecord <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_ca17e65fd4bd4d81ac8af455b0398d52</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_ca17e65fd4bd4d81ac8af455b0398d52</doaj_id><sourcerecordid>2530183465</sourcerecordid><originalsourceid>FETCH-LOGICAL-c472t-3ffa85edc9fb61269cb7cff80dab0eb65b1144dd0f8a5332bd4180137ce8d7ee3</originalsourceid><addsrcrecordid>eNpdkUtrFTEYhoMottRu_AEy4EaEo7knsxFKbxYKulBxF3L50uaQmRyTOYX-e1NPra1ZJB_Jw8NLXoReE_yBsRF_nBKhmGMmyDO0T7GiKynlz-eP5j102Noa96XU2LeXaI8xjYWWZB-dnaS2Kc26DMNXmH3Kw3m1m-u0wHCawS-1BBhiqcNJKm1K8_Cj5MVOEyw1-eFotvm2pfYKvYg2Nzi8Pw_Q97PTb8efV5dfzi-Ojy5Xniu6rFiMVgsIfoxOEipH75SPUeNgHQYnhSOE8xBw1FYwRl3gRGPClAcdFAA7QBc7byh2bTY1TbbemmKT-XNR6pWxdUk-g_GWKJAiBt4tQRPrtY1cCIfZqIOg3fVp59ps3dQzwbxUm59In77M6dpclRujseSMjF3w7l5Qy68ttMVMqXnI2c5Qts1QgbWQSlDV0bf_oeuyrf3z7iiGiWZcik6931G-ltYqxIcwBJu7ts2_tjv85nH8B_Rvt-w3fSilwA</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2530183465</pqid></control><display><type>article</type><title>Disposable Pencil Graphite Electrode for Diosmin Voltammetric Analysis</title><source>Publicly Available Content (ProQuest)</source><source>PubMed Central</source><creator>David, Iulia Gabriela ; Oancea, Alexandra-Gabriela ; Buleandră, Mihaela ; Popa, Dana Elena ; Iorgulescu, Emilia Elena ; Ciobanu, Adela Magdalena</creator><creatorcontrib>David, Iulia Gabriela ; Oancea, Alexandra-Gabriela ; Buleandră, Mihaela ; Popa, Dana Elena ; Iorgulescu, Emilia Elena ; Ciobanu, Adela Magdalena</creatorcontrib><description>Diosmin (DIO) is a naturally occurring flavonoid with multiple beneficial effects on human health. The presence of different hydroxyl groups in diosmin structure enables its electrochemical investigation and quantification. This work presents, for the first time, diosmin voltammetric behavior and quantification on the cost-effective, disposable pencil graphite electrode (PGE). Diosmin oxidation on PGE involves two irreversible steps, generating products with reversible redox behaviors. All electrode processes are pH-dependent and predominantly adsorption-controlled. Differential pulse (DPV) and adsorptive stripping differential pulse (AdSDPV) voltammetric methods have been optimized for diosmin quantification o an H-type PGE, in 0.100 mol/L H SO . The linear ranges and limits of detection were for DPV 1.00 × 10 -1.00 × 10 mol/L and 2.76 × 10 mol/L DIO for DPV and 1.00 × 10 -2.50 × 10 mol/L and 7.42 × 10 mol/L DIO for AdSDPV, respectively. The DPV method was successfully applied for diosmin quantification in dietary supplement tablets. The percentage recovery was 99.87 ± 4.88%.</description><identifier>ISSN: 2072-666X</identifier><identifier>EISSN: 2072-666X</identifier><identifier>DOI: 10.3390/mi12040351</identifier><identifier>PMID: 33805861</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>adsorptive stripping voltammetry ; Adsorptivity ; Alzheimer's disease ; Carbon ; cyclic voltammetry ; Dietary supplements ; differential pulse voltammetry ; diosmin ; disposable working electrode ; Electrodes ; Electrolytes ; Graphite ; Hydroxyl groups ; Investigations ; Memory ; Oxidation ; pencil graphite electrode ; Reagents ; Sulfuric acid ; Tumor necrosis factor-TNF ; Voltammetry</subject><ispartof>Micromachines (Basel), 2021-03, Vol.12 (4), p.351</ispartof><rights>2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 by the authors. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c472t-3ffa85edc9fb61269cb7cff80dab0eb65b1144dd0f8a5332bd4180137ce8d7ee3</citedby><cites>FETCH-LOGICAL-c472t-3ffa85edc9fb61269cb7cff80dab0eb65b1144dd0f8a5332bd4180137ce8d7ee3</cites><orcidid>0000-0003-2677-2642 ; 0000-0002-0639-0295 ; 0000-0003-2520-5486</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2530183465/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2530183465?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33805861$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>David, Iulia Gabriela</creatorcontrib><creatorcontrib>Oancea, Alexandra-Gabriela</creatorcontrib><creatorcontrib>Buleandră, Mihaela</creatorcontrib><creatorcontrib>Popa, Dana Elena</creatorcontrib><creatorcontrib>Iorgulescu, Emilia Elena</creatorcontrib><creatorcontrib>Ciobanu, Adela Magdalena</creatorcontrib><title>Disposable Pencil Graphite Electrode for Diosmin Voltammetric Analysis</title><title>Micromachines (Basel)</title><addtitle>Micromachines (Basel)</addtitle><description>Diosmin (DIO) is a naturally occurring flavonoid with multiple beneficial effects on human health. The presence of different hydroxyl groups in diosmin structure enables its electrochemical investigation and quantification. This work presents, for the first time, diosmin voltammetric behavior and quantification on the cost-effective, disposable pencil graphite electrode (PGE). Diosmin oxidation on PGE involves two irreversible steps, generating products with reversible redox behaviors. All electrode processes are pH-dependent and predominantly adsorption-controlled. Differential pulse (DPV) and adsorptive stripping differential pulse (AdSDPV) voltammetric methods have been optimized for diosmin quantification o an H-type PGE, in 0.100 mol/L H SO . The linear ranges and limits of detection were for DPV 1.00 × 10 -1.00 × 10 mol/L and 2.76 × 10 mol/L DIO for DPV and 1.00 × 10 -2.50 × 10 mol/L and 7.42 × 10 mol/L DIO for AdSDPV, respectively. The DPV method was successfully applied for diosmin quantification in dietary supplement tablets. The percentage recovery was 99.87 ± 4.88%.</description><subject>adsorptive stripping voltammetry</subject><subject>Adsorptivity</subject><subject>Alzheimer's disease</subject><subject>Carbon</subject><subject>cyclic voltammetry</subject><subject>Dietary supplements</subject><subject>differential pulse voltammetry</subject><subject>diosmin</subject><subject>disposable working electrode</subject><subject>Electrodes</subject><subject>Electrolytes</subject><subject>Graphite</subject><subject>Hydroxyl groups</subject><subject>Investigations</subject><subject>Memory</subject><subject>Oxidation</subject><subject>pencil graphite electrode</subject><subject>Reagents</subject><subject>Sulfuric acid</subject><subject>Tumor necrosis factor-TNF</subject><subject>Voltammetry</subject><issn>2072-666X</issn><issn>2072-666X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNpdkUtrFTEYhoMottRu_AEy4EaEo7knsxFKbxYKulBxF3L50uaQmRyTOYX-e1NPra1ZJB_Jw8NLXoReE_yBsRF_nBKhmGMmyDO0T7GiKynlz-eP5j102Noa96XU2LeXaI8xjYWWZB-dnaS2Kc26DMNXmH3Kw3m1m-u0wHCawS-1BBhiqcNJKm1K8_Cj5MVOEyw1-eFotvm2pfYKvYg2Nzi8Pw_Q97PTb8efV5dfzi-Ojy5Xniu6rFiMVgsIfoxOEipH75SPUeNgHQYnhSOE8xBw1FYwRl3gRGPClAcdFAA7QBc7byh2bTY1TbbemmKT-XNR6pWxdUk-g_GWKJAiBt4tQRPrtY1cCIfZqIOg3fVp59ps3dQzwbxUm59In77M6dpclRujseSMjF3w7l5Qy68ttMVMqXnI2c5Qts1QgbWQSlDV0bf_oeuyrf3z7iiGiWZcik6931G-ltYqxIcwBJu7ts2_tjv85nH8B_Rvt-w3fSilwA</recordid><startdate>20210325</startdate><enddate>20210325</enddate><creator>David, Iulia Gabriela</creator><creator>Oancea, Alexandra-Gabriela</creator><creator>Buleandră, Mihaela</creator><creator>Popa, Dana Elena</creator><creator>Iorgulescu, Emilia Elena</creator><creator>Ciobanu, Adela Magdalena</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SP</scope><scope>7TB</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>HCIFZ</scope><scope>L6V</scope><scope>L7M</scope><scope>M7S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-2677-2642</orcidid><orcidid>https://orcid.org/0000-0002-0639-0295</orcidid><orcidid>https://orcid.org/0000-0003-2520-5486</orcidid></search><sort><creationdate>20210325</creationdate><title>Disposable Pencil Graphite Electrode for Diosmin Voltammetric Analysis</title><author>David, Iulia Gabriela ; Oancea, Alexandra-Gabriela ; Buleandră, Mihaela ; Popa, Dana Elena ; Iorgulescu, Emilia Elena ; Ciobanu, Adela Magdalena</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c472t-3ffa85edc9fb61269cb7cff80dab0eb65b1144dd0f8a5332bd4180137ce8d7ee3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>adsorptive stripping voltammetry</topic><topic>Adsorptivity</topic><topic>Alzheimer's disease</topic><topic>Carbon</topic><topic>cyclic voltammetry</topic><topic>Dietary supplements</topic><topic>differential pulse voltammetry</topic><topic>diosmin</topic><topic>disposable working electrode</topic><topic>Electrodes</topic><topic>Electrolytes</topic><topic>Graphite</topic><topic>Hydroxyl groups</topic><topic>Investigations</topic><topic>Memory</topic><topic>Oxidation</topic><topic>pencil graphite electrode</topic><topic>Reagents</topic><topic>Sulfuric acid</topic><topic>Tumor necrosis factor-TNF</topic><topic>Voltammetry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>David, Iulia Gabriela</creatorcontrib><creatorcontrib>Oancea, Alexandra-Gabriela</creatorcontrib><creatorcontrib>Buleandră, Mihaela</creatorcontrib><creatorcontrib>Popa, Dana Elena</creatorcontrib><creatorcontrib>Iorgulescu, Emilia Elena</creatorcontrib><creatorcontrib>Ciobanu, Adela Magdalena</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Electronics &amp; Communications Abstracts</collection><collection>Mechanical &amp; Transportation Engineering Abstracts</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>Materials Science &amp; Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Engineering Collection</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Engineering Database</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering collection</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Micromachines (Basel)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>David, Iulia Gabriela</au><au>Oancea, Alexandra-Gabriela</au><au>Buleandră, Mihaela</au><au>Popa, Dana Elena</au><au>Iorgulescu, Emilia Elena</au><au>Ciobanu, Adela Magdalena</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Disposable Pencil Graphite Electrode for Diosmin Voltammetric Analysis</atitle><jtitle>Micromachines (Basel)</jtitle><addtitle>Micromachines (Basel)</addtitle><date>2021-03-25</date><risdate>2021</risdate><volume>12</volume><issue>4</issue><spage>351</spage><pages>351-</pages><issn>2072-666X</issn><eissn>2072-666X</eissn><abstract>Diosmin (DIO) is a naturally occurring flavonoid with multiple beneficial effects on human health. The presence of different hydroxyl groups in diosmin structure enables its electrochemical investigation and quantification. This work presents, for the first time, diosmin voltammetric behavior and quantification on the cost-effective, disposable pencil graphite electrode (PGE). Diosmin oxidation on PGE involves two irreversible steps, generating products with reversible redox behaviors. All electrode processes are pH-dependent and predominantly adsorption-controlled. Differential pulse (DPV) and adsorptive stripping differential pulse (AdSDPV) voltammetric methods have been optimized for diosmin quantification o an H-type PGE, in 0.100 mol/L H SO . The linear ranges and limits of detection were for DPV 1.00 × 10 -1.00 × 10 mol/L and 2.76 × 10 mol/L DIO for DPV and 1.00 × 10 -2.50 × 10 mol/L and 7.42 × 10 mol/L DIO for AdSDPV, respectively. The DPV method was successfully applied for diosmin quantification in dietary supplement tablets. The percentage recovery was 99.87 ± 4.88%.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>33805861</pmid><doi>10.3390/mi12040351</doi><orcidid>https://orcid.org/0000-0003-2677-2642</orcidid><orcidid>https://orcid.org/0000-0002-0639-0295</orcidid><orcidid>https://orcid.org/0000-0003-2520-5486</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2072-666X
ispartof Micromachines (Basel), 2021-03, Vol.12 (4), p.351
issn 2072-666X
2072-666X
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_ca17e65fd4bd4d81ac8af455b0398d52
source Publicly Available Content (ProQuest); PubMed Central
subjects adsorptive stripping voltammetry
Adsorptivity
Alzheimer's disease
Carbon
cyclic voltammetry
Dietary supplements
differential pulse voltammetry
diosmin
disposable working electrode
Electrodes
Electrolytes
Graphite
Hydroxyl groups
Investigations
Memory
Oxidation
pencil graphite electrode
Reagents
Sulfuric acid
Tumor necrosis factor-TNF
Voltammetry
title Disposable Pencil Graphite Electrode for Diosmin Voltammetric Analysis
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T13%3A18%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Disposable%20Pencil%20Graphite%20Electrode%20for%20Diosmin%20Voltammetric%20Analysis&rft.jtitle=Micromachines%20(Basel)&rft.au=David,%20Iulia%20Gabriela&rft.date=2021-03-25&rft.volume=12&rft.issue=4&rft.spage=351&rft.pages=351-&rft.issn=2072-666X&rft.eissn=2072-666X&rft_id=info:doi/10.3390/mi12040351&rft_dat=%3Cproquest_doaj_%3E2530183465%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c472t-3ffa85edc9fb61269cb7cff80dab0eb65b1144dd0f8a5332bd4180137ce8d7ee3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2530183465&rft_id=info:pmid/33805861&rfr_iscdi=true