Comparative evaluation of incidence of emergence agitation and post-operative recovery profile in paediatric patients after isoflurane, sevoflurane and desflurane anaesthesia

Emergence agitation (EA), although well documented in the clinical literature, still has uncertainties and confusion abound on this subject because of the absence of a clear definition and lack of reliable and valid assessment tools. To compare the incidence and severity of EA and recovery character...

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Bibliographic Details
Published in:Indian journal of anaesthesia 2012-03, Vol.56 (2), p.156-161
Main Authors: Singh, Rahil, Kharbanda, Meera, Sood, Nishant, Mahajan, Vikram, Chatterji, Chitra
Format: Article
Language:English
Subjects:
Analgesics
Behavior
Blood pressure
Clinical Investigation
desflurane
Emergence agitation
isoflurane
Otolaryngology
paediatrics
Pain
sevoflurane
Surgery
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Summary:Emergence agitation (EA), although well documented in the clinical literature, still has uncertainties and confusion abound on this subject because of the absence of a clear definition and lack of reliable and valid assessment tools. To compare the incidence and severity of EA and recovery characteristics in paediatric patients under isoflurane, sevoflurane or desflurane anaesthesia and evaluate the effect of age and duration of anaesthesia on the incidence of EA. Randomized prospective double-blinded study. Seventy-five American Society of Anaesthesiologists I and II patients, aged between 4 months and 7 years, were included in the study. Patients were induced with sevoflurane and oxygen. Anaesthesia was maintained with O(2) + N(2)O and isoflurane, sevoflurane or desflurane according to randomization. Caudal block and paracetamol suppository was administered before the surgical incision. In the Post-Anesthesia Care Unit (PACU), degree of agitation was assessed using the Paediatric Anaesthesia Emergence Delirium Scale. Aldrette score, Face, Legs, Activity, Cry, Consolability score and any adverse events were noted. Chi-square/Fischer exact test was applied for categorical variables; for continuous variables, the analysis of variance/non-parametric Kruskall-Wallis test was applied. Two-sample t-test/non-parametric Wisconsin Mann-Whitney test was applied between the two groups. Statistical significance was determined at P
ISSN:0019-5049
0976-2817
DOI:10.4103/0019-5049.96325