Postextractive Alveolar Ridge Preservation Using L-PRF: Clinical and Histological Evaluation

Leukocyte- and platelet-rich fibrin (L-PRF) is an autologous platelet concentrate rich in growth factors and plasma proteins, obtained by centrifugation of patient whole blood, and widely used in oral surgery. This report describes a case of alveolar ridge preservation with L-PRF membranes. Postextr...

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Published in:Case reports in dentistry 2020-06, Vol.2020 (2020), p.1-6
Main Authors: De Biase, Alberto, Riminucci, Mara, Di Nardo, Dario, Lamazza, Luca, Mazzucchi, Giulia, Fortunato, Lorenzo, Lollobrigida, Marco, Serafini, Giorgio, Vozza, Iole
Format: Article
Language:English
Subjects:
Anticoagulants
Autografts
Biopsy
Blood platelets
Bone grafts
Bone healing
Case Report
Case reports
Centrifugation
Ethylenediaminetetraacetic acid
Fibrin
Growth factors
Implant dentures
Inflammation
Membranes
Patients
Plasma proteins
Platelets
Rehabilitation
Soft tissues
Surgery
Systematic review
Teeth
Tooth extractions
Transplants & implants
Wound healing
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creator De Biase, Alberto
Riminucci, Mara
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Serafini, Giorgio
Vozza, Iole
description Leukocyte- and platelet-rich fibrin (L-PRF) is an autologous platelet concentrate rich in growth factors and plasma proteins, obtained by centrifugation of patient whole blood, and widely used in oral surgery. This report describes a case of alveolar ridge preservation with L-PRF membranes. Postextractive alveolar healing was then assessed through a histologic and histomorphometric analysis. A patient requiring tooth extraction and subsequent implant rehabilitation was treated with simple extraction and socket filling with L-PRF membranes. Implant placement was performed at 3 months, and a bone biopsy was obtained for histomorphometric analysis. Histological examination of the grafted sites showed that the use of L-PRF could achieve good results in terms of bone dimension and quality and soft tissue healing. The results of this study support the use of L-PRF membranes to preserve hard and soft tissues after tooth extraction.
doi_str_mv 10.1155/2020/5073519
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subjects Anticoagulants
Autografts
Biopsy
Blood platelets
Bone grafts
Bone healing
Case Report
Case reports
Centrifugation
Ethylenediaminetetraacetic acid
Fibrin
Growth factors
Implant dentures
Inflammation
Membranes
Patients
Plasma proteins
Platelets
Rehabilitation
Soft tissues
Surgery
Systematic review
Teeth
Tooth extractions
Transplants & implants
Wound healing
title Postextractive Alveolar Ridge Preservation Using L-PRF: Clinical and Histological Evaluation
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