Loading…

The Role of Trace Elements in Cardiovascular Diseases

Essential trace elements play an important role in human physiology and are associated with various functions regulating cellular metabolism. Non-essential trace elements, on the other hand, often have well-documented toxicities that are dangerous for the initiation and development of diseases due t...

Full description

Saved in:

Bibliographic Details
Published in:	Toxics (Basel) 2023-11, Vol.11 (12), p.956
Main Authors:	Wechselberger, Christian, Messner, Barbara, Bernhard, David
Format:	Article
Language:	English
Subjects:	Bioaccumulation cadmium cardiovascular disease Cardiovascular diseases Cardiovascular system Chronic exposure Cytochrome Development and progression Environmental aspects Environmental hazards Enzymes Free radicals Health aspects Heavy metals Low concentrations Metabolism Micropollutants Molybdenum Oxidation Physiology Proteins Review Roles Selenium Toxicity Trace elements Trace elements (nutrients)
Citations:	Items that this one cites Items that cite this one
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

cited_by	cdi_FETCH-LOGICAL-c552t-dbe0616aa133485018832b7de3db7c3ee3ab0889fdd75a4775a0d67bd4da243
cites	cdi_FETCH-LOGICAL-c552t-dbe0616aa133485018832b7de3db7c3ee3ab0889fdd75a4775a0d67bd4da243
container_end_page
container_issue	12
container_start_page	956
container_title	Toxics (Basel)
container_volume	11
creator	Wechselberger, Christian Messner, Barbara Bernhard, David
description	Essential trace elements play an important role in human physiology and are associated with various functions regulating cellular metabolism. Non-essential trace elements, on the other hand, often have well-documented toxicities that are dangerous for the initiation and development of diseases due to their widespread occurrence in the environment and their accumulation in living organisms. Non-essential trace elements are therefore regarded as serious environmental hazards that are harmful to health even in low concentrations. Many representatives of these elements are present as pollutants in our environment, and many people may be exposed to significant amounts of these substances over the course of their lives. Among the most common non-essential trace elements are heavy metals, which are also associated with acute poisoning in humans. When these elements accumulate in the body over years of chronic exposure, they often cause severe health damage in a variety of tissues and organs. In this review article, the role of selected essential and non-essential trace elements and their role in the development of exemplary pathophysiological processes in the cardiovascular system will be examined in more detail.
doi_str_mv	10.3390/toxics11120956
format	article
fullrecord	<record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_cb47389293b846c08c3759e28258b2e6</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A779344630</galeid><doaj_id>oai_doaj_org_article_cb47389293b846c08c3759e28258b2e6</doaj_id><sourcerecordid>A779344630</sourcerecordid><originalsourceid>FETCH-LOGICAL-c552t-dbe0616aa133485018832b7de3db7c3ee3ab0889fdd75a4775a0d67bd4da243</originalsourceid><addsrcrecordid>eNptkt9rFDEQxxdRbKl99VEWfPHl2iSTn09SzqqFgqD3HrLJ7DXH3qYmu6X-9-ba2vakCSRh8pnvZCbTNO8pOQEw5HRKt9EXSikjRshXzSEDIhYSCH_97HzQHJeyIXUYClrKt80BaAoAQh02YnWF7c80YJv6dpWdx_Z8wC2OU2nj2C5dDjHduOLnweX2SyzoCpZ3zZveDQWPH_aj5tfX89Xy--Lyx7eL5dnlwgvBpkXokEgqnavRuBaEag2sUwEhdMoDIriOaG36EJRwXNWFBKm6wINjHI6ai3vVkNzGXue4dfmPTS7aO0PKa-vyFP2A1ndcgTbMQKe59ER7UMIg00zojqGsWp_vta7nbovB1wSzG_ZE92_GeGXX6cZSorgid6_59KCQ0-8Zy2S3sXgcBjdimotlhghBBdOqoh__QzdpzmOt1I7iBhhI9kStXc0gjn2qgf1O1J4pZYDz-nuVOnmBqjPgNvo0Yh-r_SUHn1MpGfvHJCmxu7ax-21THT48L80j_q9J4C-gRLrl</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2904932362</pqid></control><display><type>article</type><title>The Role of Trace Elements in Cardiovascular Diseases</title><source>Publicly Available Content (ProQuest)</source><source>PubMed Central</source><creator>Wechselberger, Christian ; Messner, Barbara ; Bernhard, David</creator><creatorcontrib>Wechselberger, Christian ; Messner, Barbara ; Bernhard, David</creatorcontrib><description>Essential trace elements play an important role in human physiology and are associated with various functions regulating cellular metabolism. Non-essential trace elements, on the other hand, often have well-documented toxicities that are dangerous for the initiation and development of diseases due to their widespread occurrence in the environment and their accumulation in living organisms. Non-essential trace elements are therefore regarded as serious environmental hazards that are harmful to health even in low concentrations. Many representatives of these elements are present as pollutants in our environment, and many people may be exposed to significant amounts of these substances over the course of their lives. Among the most common non-essential trace elements are heavy metals, which are also associated with acute poisoning in humans. When these elements accumulate in the body over years of chronic exposure, they often cause severe health damage in a variety of tissues and organs. In this review article, the role of selected essential and non-essential trace elements and their role in the development of exemplary pathophysiological processes in the cardiovascular system will be examined in more detail.</description><identifier>ISSN: 2305-6304</identifier><identifier>EISSN: 2305-6304</identifier><identifier>DOI: 10.3390/toxics11120956</identifier><identifier>PMID: 38133357</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Bioaccumulation ; cadmium ; cardiovascular disease ; Cardiovascular diseases ; Cardiovascular system ; Chronic exposure ; Cytochrome ; Development and progression ; Environmental aspects ; Environmental hazards ; Enzymes ; Free radicals ; Health aspects ; Heavy metals ; Low concentrations ; Metabolism ; Micropollutants ; Molybdenum ; Oxidation ; Physiology ; Proteins ; Review ; Roles ; Selenium ; Toxicity ; Trace elements ; Trace elements (nutrients)</subject><ispartof>Toxics (Basel), 2023-11, Vol.11 (12), p.956</ispartof><rights>COPYRIGHT 2023 MDPI AG</rights><rights>2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2023 by the authors. 2023</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c552t-dbe0616aa133485018832b7de3db7c3ee3ab0889fdd75a4775a0d67bd4da243</citedby><cites>FETCH-LOGICAL-c552t-dbe0616aa133485018832b7de3db7c3ee3ab0889fdd75a4775a0d67bd4da243</cites><orcidid>0000-0002-2164-3019 ; 0000-0001-8331-6497</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2904932362/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2904932362?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,74998</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38133357$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wechselberger, Christian</creatorcontrib><creatorcontrib>Messner, Barbara</creatorcontrib><creatorcontrib>Bernhard, David</creatorcontrib><title>The Role of Trace Elements in Cardiovascular Diseases</title><title>Toxics (Basel)</title><addtitle>Toxics</addtitle><description>Essential trace elements play an important role in human physiology and are associated with various functions regulating cellular metabolism. Non-essential trace elements, on the other hand, often have well-documented toxicities that are dangerous for the initiation and development of diseases due to their widespread occurrence in the environment and their accumulation in living organisms. Non-essential trace elements are therefore regarded as serious environmental hazards that are harmful to health even in low concentrations. Many representatives of these elements are present as pollutants in our environment, and many people may be exposed to significant amounts of these substances over the course of their lives. Among the most common non-essential trace elements are heavy metals, which are also associated with acute poisoning in humans. When these elements accumulate in the body over years of chronic exposure, they often cause severe health damage in a variety of tissues and organs. In this review article, the role of selected essential and non-essential trace elements and their role in the development of exemplary pathophysiological processes in the cardiovascular system will be examined in more detail.</description><subject>Bioaccumulation</subject><subject>cadmium</subject><subject>cardiovascular disease</subject><subject>Cardiovascular diseases</subject><subject>Cardiovascular system</subject><subject>Chronic exposure</subject><subject>Cytochrome</subject><subject>Development and progression</subject><subject>Environmental aspects</subject><subject>Environmental hazards</subject><subject>Enzymes</subject><subject>Free radicals</subject><subject>Health aspects</subject><subject>Heavy metals</subject><subject>Low concentrations</subject><subject>Metabolism</subject><subject>Micropollutants</subject><subject>Molybdenum</subject><subject>Oxidation</subject><subject>Physiology</subject><subject>Proteins</subject><subject>Review</subject><subject>Roles</subject><subject>Selenium</subject><subject>Toxicity</subject><subject>Trace elements</subject><subject>Trace elements (nutrients)</subject><issn>2305-6304</issn><issn>2305-6304</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptkt9rFDEQxxdRbKl99VEWfPHl2iSTn09SzqqFgqD3HrLJ7DXH3qYmu6X-9-ba2vakCSRh8pnvZCbTNO8pOQEw5HRKt9EXSikjRshXzSEDIhYSCH_97HzQHJeyIXUYClrKt80BaAoAQh02YnWF7c80YJv6dpWdx_Z8wC2OU2nj2C5dDjHduOLnweX2SyzoCpZ3zZveDQWPH_aj5tfX89Xy--Lyx7eL5dnlwgvBpkXokEgqnavRuBaEag2sUwEhdMoDIriOaG36EJRwXNWFBKm6wINjHI6ai3vVkNzGXue4dfmPTS7aO0PKa-vyFP2A1ndcgTbMQKe59ER7UMIg00zojqGsWp_vta7nbovB1wSzG_ZE92_GeGXX6cZSorgid6_59KCQ0-8Zy2S3sXgcBjdimotlhghBBdOqoh__QzdpzmOt1I7iBhhI9kStXc0gjn2qgf1O1J4pZYDz-nuVOnmBqjPgNvo0Yh-r_SUHn1MpGfvHJCmxu7ax-21THT48L80j_q9J4C-gRLrl</recordid><startdate>20231123</startdate><enddate>20231123</enddate><creator>Wechselberger, Christian</creator><creator>Messner, Barbara</creator><creator>Bernhard, David</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7U7</scope><scope>7XB</scope><scope>8FE</scope><scope>8FH</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-2164-3019</orcidid><orcidid>https://orcid.org/0000-0001-8331-6497</orcidid></search><sort><creationdate>20231123</creationdate><title>The Role of Trace Elements in Cardiovascular Diseases</title><author>Wechselberger, Christian ; Messner, Barbara ; Bernhard, David</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c552t-dbe0616aa133485018832b7de3db7c3ee3ab0889fdd75a4775a0d67bd4da243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Bioaccumulation</topic><topic>cadmium</topic><topic>cardiovascular disease</topic><topic>Cardiovascular diseases</topic><topic>Cardiovascular system</topic><topic>Chronic exposure</topic><topic>Cytochrome</topic><topic>Development and progression</topic><topic>Environmental aspects</topic><topic>Environmental hazards</topic><topic>Enzymes</topic><topic>Free radicals</topic><topic>Health aspects</topic><topic>Heavy metals</topic><topic>Low concentrations</topic><topic>Metabolism</topic><topic>Micropollutants</topic><topic>Molybdenum</topic><topic>Oxidation</topic><topic>Physiology</topic><topic>Proteins</topic><topic>Review</topic><topic>Roles</topic><topic>Selenium</topic><topic>Toxicity</topic><topic>Trace elements</topic><topic>Trace elements (nutrients)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wechselberger, Christian</creatorcontrib><creatorcontrib>Messner, Barbara</creatorcontrib><creatorcontrib>Bernhard, David</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Toxicology Abstracts</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>Biological Sciences</collection><collection>ProQuest Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>Toxics (Basel)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wechselberger, Christian</au><au>Messner, Barbara</au><au>Bernhard, David</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Role of Trace Elements in Cardiovascular Diseases</atitle><jtitle>Toxics (Basel)</jtitle><addtitle>Toxics</addtitle><date>2023-11-23</date><risdate>2023</risdate><volume>11</volume><issue>12</issue><spage>956</spage><pages>956-</pages><issn>2305-6304</issn><eissn>2305-6304</eissn><abstract>Essential trace elements play an important role in human physiology and are associated with various functions regulating cellular metabolism. Non-essential trace elements, on the other hand, often have well-documented toxicities that are dangerous for the initiation and development of diseases due to their widespread occurrence in the environment and their accumulation in living organisms. Non-essential trace elements are therefore regarded as serious environmental hazards that are harmful to health even in low concentrations. Many representatives of these elements are present as pollutants in our environment, and many people may be exposed to significant amounts of these substances over the course of their lives. Among the most common non-essential trace elements are heavy metals, which are also associated with acute poisoning in humans. When these elements accumulate in the body over years of chronic exposure, they often cause severe health damage in a variety of tissues and organs. In this review article, the role of selected essential and non-essential trace elements and their role in the development of exemplary pathophysiological processes in the cardiovascular system will be examined in more detail.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>38133357</pmid><doi>10.3390/toxics11120956</doi><orcidid>https://orcid.org/0000-0002-2164-3019</orcidid><orcidid>https://orcid.org/0000-0001-8331-6497</orcidid><oa>free_for_read</oa></addata></record>
fulltext	fulltext
identifier	ISSN: 2305-6304
ispartof	Toxics (Basel), 2023-11, Vol.11 (12), p.956
issn	2305-6304 2305-6304
language	eng
recordid	cdi_doaj_primary_oai_doaj_org_article_cb47389293b846c08c3759e28258b2e6
source	Publicly Available Content (ProQuest); PubMed Central
subjects	Bioaccumulation cadmium cardiovascular disease Cardiovascular diseases Cardiovascular system Chronic exposure Cytochrome Development and progression Environmental aspects Environmental hazards Enzymes Free radicals Health aspects Heavy metals Low concentrations Metabolism Micropollutants Molybdenum Oxidation Physiology Proteins Review Roles Selenium Toxicity Trace elements Trace elements (nutrients)
title	The Role of Trace Elements in Cardiovascular Diseases
url	http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T22%3A38%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20Role%20of%20Trace%20Elements%20in%20Cardiovascular%20Diseases&rft.jtitle=Toxics%20(Basel)&rft.au=Wechselberger,%20Christian&rft.date=2023-11-23&rft.volume=11&rft.issue=12&rft.spage=956&rft.pages=956-&rft.issn=2305-6304&rft.eissn=2305-6304&rft_id=info:doi/10.3390/toxics11120956&rft_dat=%3Cgale_doaj_%3EA779344630%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c552t-dbe0616aa133485018832b7de3db7c3ee3ab0889fdd75a4775a0d67bd4da243%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2904932362&rft_id=info:pmid/38133357&rft_galeid=A779344630&rfr_iscdi=true