Delirium in the ICU: how much do we know? A narrative review

Delirium in critical ill patients is a complex and common neurological syndrome in the intensive care unit (ICU) that is caused by a range of structural or functional abnormalities. ICU Delirium is associated with reduced compliance, prolonged hospital stays, greater use or delayed withdrawal of sed...

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Bibliographic Details
Published in:Annals of medicine (Helsinki) 2024-12, Vol.56 (1), p.2405072
Main Authors: Liu, Si Bo, Wu, Hong Yu, Duan, Mei Li, Yang, Rong Li, Ji, Chen Hua, Liu, Jin Jie, Zhao, Hongtao
Format: Article
Language:English
Subjects:
Biomarkers
Delirium
Delirium - diagnostic imaging
Delirium - pathology
Delirium - therapy
diagnosis
Humans
intensive care unit
Intensive Care Units - statistics & numerical data
Metabolic Diseases - diagnosis
Nervous System Diseases - diagnostic imaging
Neurology
Review
treatment
Citations: Items that this one cites
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Summary:Delirium in critical ill patients is a complex and common neurological syndrome in the intensive care unit (ICU) that is caused by a range of structural or functional abnormalities. ICU Delirium is associated with reduced compliance, prolonged hospital stays, greater use or delayed withdrawal of sedatives, higher rates and durations of mechanical ventilation, and higher rates of mortality. The aetiology and pathogenesis of ICU delirium are unclear, and the lack of better prediction, prevention, and treatment measures leads to a non-standardized control of delirium. By searching the relevant literature, we aim in this narrative review to describe progress in the pathogenesis, predictive biomarkers, diagnosis, and treatment of ICU delirium.
ISSN:0785-3890
1365-2060
1365-2060
DOI:10.1080/07853890.2024.2405072