Tuning the Toxicity of Reactive Oxygen Species into Advanced Tumor Therapy

The biological functions and toxic effects of reactive oxygen species (ROS) are generally entangled. A large amount of ROS may cause oxidative damage to cell biomolecules, leading to cell death. Tumor treatment can be carried out by using the toxicity of ROS, and various nanosystems related to ROS h...

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Bibliographic Details
Published in:Nanoscale research letters 2021-09, Vol.16 (1), p.142-142, Article 142
Main Authors: Xie, An, Li, He, Hao, Yumei, Zhang, Yujia
Format: Article
Language:English
Subjects:
Apoptosis
Biomolecules
Cancer therapies
Cell death
Chemistry and Materials Science
Chemodynamic therapy
Materials Science
Microenvironments
Molecular Medicine
Nano Review
Nanochemistry
Nanoscale Science and Technology
Nanotechnology
Nanotechnology and Microengineering
Oxygen
Photodynamic therapy
Reactive oxygen species
Toxicity
Tumor therapy
Tumors
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Summary:The biological functions and toxic effects of reactive oxygen species (ROS) are generally entangled. A large amount of ROS may cause oxidative damage to cell biomolecules, leading to cell death. Tumor treatment can be carried out by using the toxicity of ROS, and various nanosystems related to ROS have been designed. In fact, the level of active oxygen in the biological microenvironment can be regulated in advanced therapeutics via designed nanoscale engineering, which can open up a new direction of treatment with specific simplicity. In this progress report, the authors first introduced how ROS causes cell death. Then, recent studies on converting the inherent toxicity from ROS into advanced treatment tools are highlighted.
ISSN:1556-276X
1931-7573
1556-276X
DOI:10.1186/s11671-021-03599-8