Post-partum acute kidney injury

• Published in: Saudi journal of kidney diseases and transplantation 2014-11, Vol.25 (6), p.1144-1147
• Main Authors: Pahwa, Naresh, Kumar, Ravindra, Bahrani, Rajesh
• Format: Article
• Language: English
• Subjects: Acute Kidney Injury - diagnosis; Acute Kidney Injury - etiology; Acute Kidney Injury - microbiology; Acute Kidney Injury - mortality; Acute Kidney Injury - therapy; Acute renal failure; Adult; Biomarkers - blood; Blood transfusions; Complications; Creatinine - blood; Developing countries; Dialysis; Enzymes; Female; Gangrene; Health aspects; Hospitals; Humans; Industrialized nations; LDCs; Length of Stay; Maternal Mortality; Mortality; Obstetrics; Patient outcomes; Postpartum Period; Preeclampsia; Pregnancy; Pregnant women; Puerperal Disorders - diagnosis; Puerperal Disorders - etiology; Puerperal Disorders - microbiology; Puerperal Disorders - mortality; Puerperal Disorders - therapy; Puerperal Infection - microbiology; Retrospective Studies; Risk Factors; Sepsis; Sepsis - microbiology; Studies; Tertiary Care Centers; Time Factors; Womens health; Young Adult; الأمراض; الحمل; الفشل الكلوي; الكلى; المرأة الحامل; المرضى; المضاعفات; الولادة; عفونة الدم
• ISSN: 1319-2442; 2320-3838
• DOI: 10.4103/1319-2442.144259

To determine the risk factors, course of hospital stay and mortality rate among women with post-partum acute kidney injury (AKI), we studied (of 752 patients with AKI admitted to a tertiary care center during the study period between November 2009 and August 2012) 27 (3.59 %) women with post-partum AKI. The data regarding age, parity, cause of renal failure, course of hospital stay and requirement of dialysis were recorded. Sepsis was the major cause (70.3 %) of post-partum AKI. Other causes included disseminated intravascular coagulation (55.5 %), pre-eclampsia/eclampsia (40.7 %), ante- and post-partum hemorrhage (40.7 % and 22.2 %) and hemolytic anemia and elevated liver enzymes and low platelet count syndrome (29.6 %) ; most patients had more than one cause of AKI. We found a very high prevalence (18.5 %) of cortical necrosis in our study patients. A significant correlation was also found between the creatinine level on admission and the period of onset of disease after delivery. In conclusion, several factors are involved in causing post-partum AKI in our population, and sepsis was the most common of them.