Incidental Merkel cell carcinoma in a cutaneous horn: a case report

Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy, which usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin. We present a 93-year-old female who presented with a "cutaneous horn" on the face. On excision, histologic examination rev...

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Bibliographic Details
Published in:Dermatology practical & conceptual 2015-01, Vol.5 (1), p.47-60
Main Authors: Schick, Brian A, Tobe, Joshua S, Joseph, Mariamma G, Rouse, Tyler B, Gabril, Manal Y
Format: Article
Language:English
Subjects:
cutaneous horn
Merkel cell carcinoma
Original Research
squamous cell carcinoma
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Summary:Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy, which usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin. We present a 93-year-old female who presented with a "cutaneous horn" on the face. On excision, histologic examination revealed a combined squamous cell carcinoma in situ with underlying MCC. Merkel cell polyomavirus immunohistochemistry was negative in this lesion. This case report highlights the significant association between MCC and squamous cell carcinoma and the uncommon clinical presentation of this combined tumor in the form of a cutaneous horn.
ISSN:2160-9381
2160-9381
DOI:10.5826/dpc.0501a08