A proof-of-concept study of cascade screening for Familial Hypercholesterolemia in the US, adapted from the Dutch model

The Dutch cascade screening model for FH was the most successful of such programs in the world. It remains unclear whether aspects of the Dutch model (i.e. direct engagement with FH probands and relatives outside usual healthcare settings) are feasible in the US. This is especially important since p...

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Bibliographic Details
Published in:American journal of preventive cardiology 2021-06, Vol.6, p.100170-100170, Article 100170
Main Authors: McGowan, Mary P., Cuchel, Marina, Ahmed, Catherine D., Khera, Amit, Weintraub, William S., Wilemon, Katherine A., Ahmad, Zahid
Format: Article
Language:English
Subjects:
Cascade screening
Cholesterol
Dutch lipid clinic network
Familial hypercholesterolemia
Family screening
Hypercholesterolemia dyslipidemia
Hyperlipidemia
LDLR
Severe hypercholesterolemia
Short Report
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Summary:The Dutch cascade screening model for FH was the most successful of such programs in the world. It remains unclear whether aspects of the Dutch model (i.e. direct engagement with FH probands and relatives outside usual healthcare settings) are feasible in the US. This is especially important since prior attempts at cascade screening in the US have had very low screening rates (
ISSN:2666-6677
2666-6677
DOI:10.1016/j.ajpc.2021.100170