Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms

In pharmaceutical sciences, visual inspection is one of the oldest methods used for description in pharmacopeias and is still an important part of the characterization and qualification of active ingredients, excipients, and dosage forms. With the development of technology, it is now also possible t...

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Bibliographic Details
Published in:Pharmaceutics 2021-05, Vol.13 (5), p.685
Main Authors: Farkas, Dóra, Madarász, Lajos, Nagy, Zsombor K., Antal, István, Kállai-Szabó, Nikolett
Format: Article
Language:English
Subjects:
Automation
Deep learning
foam
image analysis
Manufacturing
Methods
Microscopy
Morphology
Particle size
pharmaceutical dosage form
Pharmaceutical industry
Process controls
Quality control
Review
shape parameters
Software
Vision systems
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Summary:In pharmaceutical sciences, visual inspection is one of the oldest methods used for description in pharmacopeias and is still an important part of the characterization and qualification of active ingredients, excipients, and dosage forms. With the development of technology, it is now also possible to take images of various pharmaceutical dosage forms with different imaging methods in a size range that is hardly visible or completely invisible to the human eye. By analyzing high-quality designs, physicochemical processes can be understood, and the results can be used even in the optimization of the composition of the dosage form and in the development of its production. The present study aims to show some of the countless ways image analysis can be used in the manufacturing and quality assessment of different dosage forms. This summary also includes measurements and an evaluation of, amongst others, a less studied dosage form, medicated foams.
ISSN:1999-4923
1999-4923
DOI:10.3390/pharmaceutics13050685