Chylothorax after pulmonary resection and lymph node dissection for primary lung cancer; retrospective observational study

• Published in: Journal of cardiothoracic surgery 2022-01, Vol.17 (1), p.11-11, Article 11
• Main Authors: Yasuura, Yoshiyuki, Konno, Hayato, Hayakawa, Takamitsu, Terada, Yukihiro, Mizuno, Kiyomichi, Kayata, Hiroyuki, Kojima, Hideaki, Mizuno, Tetsuya, Isaka, Mitsuhiro, Ohde, Yasuhisa
• Format: Article
• Language: English
• Subjects: Adult; Aged; Aged, 80 and over; Cancer; Cancer therapies; Care and treatment; Chest tubes; Chylothorax; Chylothorax - etiology; Chylothorax - surgery; Complications; Diet; Dissection; Female; Health aspects; Humans; Low fat diet; Lung cancer; Lung Neoplasms - surgery; Lymph node dissection; Lymph Node Excision - adverse effects; Lymph nodes; Lymphatic system; Male; Metastasis; Middle Aged; Nutrient deficiency; Nutrition research; Observational studies; Oncology, Experimental; Parenteral nutrition; Patients; Pleural effusion; Pneumonectomy - adverse effects; Postoperative; Postoperative Complications; Primary lung cancer; Pulmonary resection; Respiratory agents; Retrospective Studies; Surgery; Surgical drains; Thoracic surgery; Triglycerides; Wound drainage
• ISSN: 1749-8090; 1749-8090
• DOI: 10.1186/s13019-022-01758-1

Pulmonary resection with mediastinal lymph node dissection for treating primary lung cancer could sometimes causes chylothorax as a postoperative complication. This study examined the validity of treatments for chylothorax in our hospital. We evaluated 2019 patients who underwent lobectomy, bilobectomy, or pneumonectomy with mediastinal lymph node dissection for primary lung cancer at Shizuoka Cancer Center Hospital, Shizuoka, Japan, between September 2002 and March 2018. The diagnostic criteria for postoperative chylothorax were that the drainage from the pleural drain was evidently white and turbid, or the pleural effusion contained a triglyceride level of > 110 mg/dL. The clinical courses and treatments were retrospectively reviewed. Postoperative chylothorax occurred in 37 patients (1.8%), 20 men and 17 women, with a median age of 70 years (33-80). A low-fat diet was instituted to all patients; 35 cases improved with conservative treatment, and 2 cases required reoperation. Nine cases had a drainage volume ≥ 500 mL one day following the low-fat diet commencement, which was resolved with conservative treatment and decreased drainage was observed on the third day of treatment in seven of those cases. Two cases with excessive drainage of ≥ 1000 mL in one day and systemic symptoms associated with chyle loss needed surgery. Even when the daily drainage volume exceeds 500 mL following a low-fat diet, there were many cases that could be cured conservatively. The indication for surgery needs to be carefully considered.