Association between vitamin D deficiency and the risk of prevalent type 2 diabetes and incident prediabetes: A prospective cohort study using data from The Irish Longitudinal Study on Ageing (TILDA)

BackgroundIt is hypothesized that vitamin D contributes to the aetiology of type 2 diabetes mellitus (diabetes). This study's objective was to examine the relationships between baseline vitamin D status (as measured by plasma 25-hydroxyvitamin D concentration) and both prevalent diabetes and pr...

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Published in:EClinicalMedicine 2022-11, Vol.53, p.101654-101654, Article 101654
Main Authors: McCarthy, Kevin, Laird, Eamon, O'Halloran, Aisling M., Walsh, Cathal, Healy, Martin, Fitzpatrick, Annette L., Walsh, James B., Hernández, Belinda, Fallon, Padraic, Molloy, Anne M., Kenny, Rose Anne
Format: Article
Language:English
Subjects:
Diabetes
Prediabetes
Public health
TILDA
Vitamin D
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Summary:BackgroundIt is hypothesized that vitamin D contributes to the aetiology of type 2 diabetes mellitus (diabetes). This study's objective was to examine the relationships between baseline vitamin D status (as measured by plasma 25-hydroxyvitamin D concentration) and both prevalent diabetes and prospective risk of developing diabetes, including prediabetes, in a population with historically low levels of vitamin D. MethodsIn this prospective cohort study, data from The Irish Longitudinal Study on Ageing (TILDA), a nationally representative cohort of adults aged ≥50 years residing in Ireland were analysed, including wave 1 (October 2009-June 2011) (n = 5272) and wave 3 (March 2014-October 2015) (n = 3828). Those aged
ISSN:2589-5370
2589-5370
DOI:10.1016/j.eclinm.2022.101654