IL-34 a Newly Discovered Cytokine

In this study we describe some biological effects of IL-34, a newly discovered cytokine. We show that Il-34 stimulates monocyte cell viability and directly modulates the number and function of monocytes and regulates myeloid cell growth and differentiation. Moreover, since IL-34 in mice is involved...

Full description

Saved in:
Bibliographic Details
Published in:European journal of inflammation 2010-05, Vol.8 (2), p.63-66
Main Authors: Castellani, M.L., Anogeianaki, A., Felaco, P., Toniato, E., De Lutiis, M.A., Shaik, B., Fulcheri, M., Vecchiet, J., Tetè, S., Salini, V., Theoharides, T.C., Caraffa, A., Antinolfi, P., Frydas, S., Conti, P., Cuccurullo, C., Ciampoli, C., Cerulli, G.
Format: Article
Language:English
Subjects:
Cytokines
Citations: Items that this one cites
Items that cite this one
Online Access:Request full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this study we describe some biological effects of IL-34, a newly discovered cytokine. We show that Il-34 stimulates monocyte cell viability and directly modulates the number and function of monocytes and regulates myeloid cell growth and differentiation. Moreover, since IL-34 in mice is involved in osteoporosis, an antagonist of this cytokine could be beneficial for the treatment of this disease.
ISSN:2058-7392
1721-727X
2058-7392
DOI:10.1177/1721727X1000800202