Influence of fermented feed additive on gut morphology, immune status, and microbiota in broilers

• Published in: BMC veterinary research 2022-06, Vol.18 (1), p.218-218, Article 218
• Main Authors: Peng, Wentong, Talpur, Mir Zulqarnain, Zeng, Yuxian, Xie, Peipei, Li, Jincheng, Wang, Songbo, Wang, Lina, Zhu, Xiaotong, Gao, Ping, Jiang, Qingyan, Shu, Gang, Zhang, Haijun
• Format: Article
• Language: English
• Subjects: Analysis; Animal Feed - analysis; Animal feeding and feeds; Animals; Antibiotics; Broiler; Broilers (Poultry); Cecum; Chickens - anatomy & histology; Cytokines; Diet; Diet - veterinary; Dietary Supplements - analysis; Diseases; Dosage and administration; Duodenum; Feed additives; Feeds; Fermentation; Fermented feed; Fermented food; Gene expression; Genetic aspects; Growth; Immune status; Interleukin 1; Interleukin 10; Intestinal immunity; Jejunum; Lactobacillaceae; Lactobacillus; Microbiota; Microbiota (Symbiotic organisms); Microorganisms; Morphology; Mortality; Nutrient deficiency; Poultry; Probiotics; Production processes; Small intestine; Small intestine histology; Thymus gland; TLR4 protein; Toll-like receptors; Villus
• ISSN: 1746-6148; 1746-6148
• DOI: 10.1186/s12917-022-03322-4

This study examined the effects of a solid-state fermented feed additive (FFA) on the small intestine histology/morphology, immunity and microbiota of broilers. Two hundred eighty-eight day-old Arbor Acre chicks, were randomly assigned to one of four groups (each group has 6 replicates, with each replicate containing 12 chickens). The negative control (NC; basal diet), the positive control (PC; basal diet +antibiotic 15 ppm), the fermented feed additive low dose (FFL; basal diet + 0.3 kg/t FFA), and the fermented feed additive high dose (FFH; 3 kg/t FFA) with Lactobacillus casei (L.casei). The study found that the FFH and FFL groups gained more weight (1-21d) and the FFL and PC diets had better feed conversion ratio (P